Detailed information of TA system TA170167

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): holin-SprF1/-
• Location: 1812678..1813059
• Replicon: chromosome
• Accession: NZ_CP060271
• Organism: Staphylococcus xylosus strain DMSX03

Toxin (Protein)

• Gene name: holin
• Uniprot ID: -
• Locus tag: DMSX03_RS08540
• Protein ID: WP_155238586.1
• Coordinates: 1812678..1812845 (-)
• Length: 56 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1812899..1813059 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DMSX03_RS08520	1808111..1809994	-	1884	WP_186335303.1	glycosyltransferase	-
DMSX03_RS08525	1810680..1811189	+	510	Protein_1648	transposase	-
DMSX03_RS08530	1811247..1811495	-	249	WP_029379025.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
DMSX03_RS08535	1812181..1812297	-	117	WP_158227722.1	hypothetical protein	-
DMSX03_RS08540	1812678..1812845	-	168	WP_155238586.1	hypothetical protein	Toxin
-	1812899..1813059	+	161	-	-	Antitoxin
DMSX03_RS08545	1813289..1813450	-	162	WP_156035523.1	hypothetical protein	-
DMSX03_RS08550	1814016..1814435	-	420	WP_186335304.1	MarR family transcriptional regulator	-
DMSX03_RS08555	1814554..1815525	+	972	WP_186335305.1	acryloyl-CoA reductase	-
DMSX03_RS08560	1815574..1815984	-	411	Protein_1655	YolD-like family protein	-
DMSX03_RS08565	1816186..1816830	-	645	WP_186335306.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1808111..1862075	53964

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-97)

Sequences

Toxin

Protein

• Length: 56 a.a.
• Molecular weight: 6159.16 Da
• Isoelectric Point: 6.1184

>T170167 WP_155238586.1 NZ_CP060271:c1812845-1812678 [Staphylococcus xylosus]
MYVKVTVIARVLSLVLTLVNQRLSNKSVNPILVDESTLLTMAEPLNTTWKDDSNN

Nucleotide

• Length: 168 bp

>T170167 NZ_CP077093:c1079079-1078741 [Pseudomonas vanderleydeniana]
ATGACCCGCACGGTTTTCACCCACGCCGCCATCCGCTCGATCGACATGCAGGAACTCTATCTAGCCGACAAGGTTGGCCA
TCAAGCCGCCTCAAAGTACTTTGGTGAGCTGGAAGATGTAGAACAGCGACTCAACGATCACCCGGAATCCGGACAGCTCT
GCCTGCAAGCTGCGGAACTGGGGGCCATTCAGTATCGAGAACTGAATTACAACCCTTATCGGGTTATCTACAGCCATGAC
GCCGCCAGCGACACAGCCGTTGTGCACCTGGTATTGAATCAGGCACAAAACGTGAGGGATTGGCTGGTGCATTACTGCCT
GATCAAAGATCTCGATTGA

Antitoxin

Nucleotide

• Length: 161 bp

>AT170167 NZ_CP060271:1812899-1813059 [Staphylococcus xylosus]
TTGATAATATATTTATGTTGTGTTAATTTATAGATAGAAAAAGGGCAACACACCATAAATGTATCGCCCTAATGAGCCCG
TTAAAAAGACGGTGACCATTCTTTAATGATTATCTTTAATAACCATCGAACCGGTCAAAGTTAGCGATGGTTATTTTTTA
T

Structures

Antitoxin