Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2466669..2467210 Replicon chromosome
Accession NZ_CP060244
Organism Entomobacter blattae strain G55GP

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JGUZn3_RS11165 Protein ID WP_203413585.1
Coordinates 2466669..2466935 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JGUZn3_RS11170 Protein ID WP_203413586.1
Coordinates 2466932..2467210 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGUZn3_RS11135 2462329..2462832 + 504 WP_203413579.1 hypothetical protein -
JGUZn3_RS11140 2462829..2463863 + 1035 WP_203413580.1 hypothetical protein -
JGUZn3_RS11145 2464371..2465087 + 717 WP_203413581.1 phage antirepressor KilAC domain-containing protein -
JGUZn3_RS11150 2465102..2465383 + 282 WP_203413582.1 hypothetical protein -
JGUZn3_RS11155 2465605..2466150 + 546 WP_203413583.1 hypothetical protein -
JGUZn3_RS11160 2466204..2466668 + 465 WP_203413584.1 hypothetical protein -
JGUZn3_RS11165 2466669..2466935 - 267 WP_203413585.1 Txe/YoeB family addiction module toxin Toxin
JGUZn3_RS11170 2466932..2467210 - 279 WP_203413586.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JGUZn3_RS11175 2467515..2468306 + 792 WP_203414919.1 tyrosine-type recombinase/integrase -
JGUZn3_RS11180 2468314..2468505 + 192 WP_203413587.1 hypothetical protein -
JGUZn3_RS11185 2468979..2469599 + 621 WP_203413588.1 DUF3164 family protein -
JGUZn3_RS11190 2469589..2470350 - 762 WP_203413589.1 DUF4393 domain-containing protein -
JGUZn3_RS11195 2470375..2470704 + 330 WP_203413590.1 HNH endonuclease -
JGUZn3_RS11200 2470957..2471589 + 633 WP_203413591.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2449285..2499661 50376


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10520.02 Da        Isoelectric Point: 9.4426

>T170136 WP_203413585.1 NZ_CP060244:c2466935-2466669 [Entomobacter blattae]
MKVVFTETGWEDYLYWASHDHAMLAKVNTLVEDTRRHPFIGLGKPEALKGQLSGWWSRRITKEHRLVYRVTGTRETQQVE
IIQCRYHY

Download         Length: 267 bp

>T170136 NZ_CP077089:2072634-2072846 [Pseudomonas tensinigenes]
GTGCAGAGCAGGCTATTGATCAAGGAGCTGGAGGAGGCAGGCTGGACGCTGGATCGGGTCACCGGCAGTCATCACATCTT
CAAGCACCGATACAACCCGTACACGATTCCCGTCCCACATCTGAAAAAGGATTTGCCGTTGGGAGCGGTCAAAAGCATCA
GGAGGCGTGCCGGGTTATACAACCCGCCAGCCAGTTTCGAAGGAGATCCGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10210.34 Da        Isoelectric Point: 5.9601

>AT170136 WP_203413586.1 NZ_CP060244:c2467210-2466932 [Entomobacter blattae]
MTHVSYTDLRKNLAHYLDEAANSRAPIVVTRTSAHQNVVILSEEEFSGLQETVHLLNSPKNTQRLLKGIEQASQGKLEEH
TLITPDDTASNS

Download         Length: 279 bp

>AT170136 NZ_CP077089:2072846-2073250 [Pseudomonas tensinigenes]
ATGCAATATCCAATCTGTATCGAGTGGGGAGACGAGAACACTGCCATCGGTATTCAGATCCCCGATATTCCCGGCGCCGT
TACAGCAGGGGATAGCTTTGAAGATGCCTACAAGGCGGCGGTCGAAGTCGCCCACATCATGCTGCAGGAGATTGCGGCGG
ACGGGGAGTCGATTCCTATGCCGACTTCGGCATCCGCTCATCGCAGTAATCCGGACTTTGCCGACATGGGCTGGGGCATG
CTGGAACTGGATATTTCGCCCTATCTCGGCAAGACCGAGAAGGTCAACGTAACGCTGCCCGGTTATGTGATTCAGCGCAT
CGATCGTTATGTGCGCGAGCACAACGTCAAAAGCCGCTCCTCCTTTCTGGCCGATGCGGCGATGGAAAAGCTGGTTCGAT
ATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References