Detailed information of TA system TA170065

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1818321..1818501
• Replicon: chromosome
• Accession: NZ_CP060141
• Organism: Staphylococcus aureus strain 2868B2

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: H5U44_RS09305
• Protein ID: WP_001801861.1
• Coordinates: 1818406..1818501 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1818321..1818378 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H5U44_RS09265	1814445..1814525	+	81	Protein_1779	hypothetical protein	-
H5U44_RS09270	1814638..1814871	-	234	WP_001814019.1	IS256 family transposase	-
H5U44_RS09275	1814808..1814969	-	162	WP_240140581.1	hypothetical protein	-
H5U44_RS09280	1815158..1815250	-	93	WP_240140582.1	transposase	-
H5U44_RS09285	1815216..1815800	-	585	WP_240140523.1	transposase	-
H5U44_RS09290	1816060..1816569	+	510	WP_224684909.1	hypothetical protein	-
H5U44_RS09295	1816889..1817755	+	867	WP_234746002.1	hypothetical protein	-
H5U44_RS09300	1818185..1818283	-	99	Protein_1786	hypothetical protein	-
-	1818321..1818378	+	58	-	-	Antitoxin
H5U44_RS09305	1818406..1818501	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
H5U44_RS09310	1818953..1819399	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
H5U44_RS09315	1819513..1820139	+	627	Protein_1789	ImmA/IrrE family metallo-endopeptidase	-
H5U44_RS09320	1820271..1821023	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
H5U44_RS09325	1821050..1821733	-	684	WP_000957233.1	exotoxin beta-grasp domain-containing protein	-
H5U44_RS09330	1821820..1822446	-	627	WP_240140524.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	1797561..1825005	27444
	-	flank	IS/Tn	-	-	1815216..1815800	584

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T170065 WP_001801861.1 NZ_CP060141:c1818501-1818406 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T170065 NZ_CP077075:c5900740-5900558 [Pseudomonas xanthosomae]
ATGCGCAGCAGGGAAGTGATACAGCTCATCGAAGCCGATGGCTGGTATGAGGTGGATGTCAAAGGGAGCCATCACCAATT
CAGGCATCCCTTCAAGAAAGGTCGGGTCACGGTACCTCACCCCAAATGCGACCTGCCTCGGGGTACGGTGCACAGCATCC
TGAAACAAGCAGGCCTGAAATGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT170065 NZ_CP060141:1818321-1818378 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin