169957

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 575784..576294 Replicon chromosome
Accession NZ_CP060096
Organism Aceticella autotrophica strain 3443-3Ac

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ACETAC_RS02525 Protein ID WP_284680502.1
Coordinates 576034..576294 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ACETAC_RS02520 Protein ID WP_284680501.1
Coordinates 575784..576041 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACETAC_RS02495 (ACETAC_02475) 571152..571541 + 390 WP_284680497.1 helix-turn-helix transcriptional regulator -
ACETAC_RS02500 (ACETAC_02480) 571538..572008 + 471 WP_284680498.1 preprotein translocase subunit SecB -
ACETAC_RS02505 (ACETAC_02485) 572475..572570 + 96 Protein_485 polyphenol oxidase -
ACETAC_RS02510 (ACETAC_02490) 572701..574152 + 1452 WP_284680499.1 transposase -
ACETAC_RS02515 (ACETAC_02495) 574641..575714 + 1074 WP_284680500.1 plasmid pRiA4b ORF-3 family protein -
ACETAC_RS02520 (ACETAC_02500) 575784..576041 + 258 WP_284680501.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ACETAC_RS02525 (ACETAC_02505) 576034..576294 + 261 WP_284680502.1 Txe/YoeB family addiction module toxin Toxin
ACETAC_RS02530 (ACETAC_02510) 576536..578023 + 1488 WP_284680503.1 TIGR02677 family protein -
ACETAC_RS02535 (ACETAC_02515) 578016..579167 + 1152 WP_284680504.1 TIGR02678 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10521.98 Da        Isoelectric Point: 6.7187

>T169957 WP_284680502.1 NZ_CP060096:576034-576294 [Aceticella autotrophica]
MNKMFTDIAWEDYEYWQINDRKILKKINELIKDIDWNGNEGKGKPEPLKHELQGLWSRRITAEHRLIYKIDDKNIYILQC
RGHYDD

Download         Length: 261 bp

>T169957 NZ_CP076818:c54132-53773 [Acinetobacter baumannii]
ATGGCTTGGGATGTAGAAACAACAGAACTTTTTGATTCTTGGTTGGCAGAACAAGATGAAAATGCTCAAGATAAAATCTT
AGCGTCTTTGCTTGTTTTGTCAGAACTGGGTCCAAATCTAGGCCGGCCTCATGTTGATACTATTAAAGAATCAAAATATC
CGAACATGAAAGAGATACGTGTGCAAGTTAAAGGTCATCCGATCCGTGGTTTCTTTGCATTTGATCCAGAACGTAAAGCC
ATTGTTTTGTGTGCTGGAGATAAGAAAGGGCTAAATGAAAAAGCCTTTTATAAAGAAATGATCAAGATTGCAGATGAACA
ATATGAGCAATATTTACGTGATAATTATGGAGATAAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9972.33 Da        Isoelectric Point: 7.9455

>AT169957 WP_284680501.1 NZ_CP060096:575784-576041 [Aceticella autotrophica]
MLAVNYSNARQKFKEYCDIANKDYETIIITRKRGGNVVMLSEEEYNNIMENLFVRSDKKAYERLLKSMDQLKAGKASQRE
LDTNE

Download         Length: 258 bp

>AT169957 NZ_CP076818:c53773-53474 [Acinetobacter baumannii]
ATGGCTAAATTAAACGATATAATTTCAAAACGCTCACCTGAAAGCCAACAACGCATCAAGAAAATGGCAAATCAAATGCT
ATTGGATATTAACCTATCGAACCTACGGGAAGAGTTAAAAATATCTCAAGCTGAAATTGCAAAAAATCTAGGTGTAAGCC
AAGCTGCTATTTCAAAACGTGAAAAATTAGGTAAAGATCTTAAGATTTCATCATTAAAAGAATATGTTGAAGCTATGGGT
GGCAAAGTAAGGTTAGATGTTGAGTTACCTAACGGAAAGCATGTTGCTATATCTATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References