Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 4620945..4621167 | Replicon | chromosome |
Accession | NZ_CP059917 | ||
Organism | Escherichia coli strain 64.1 |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | A0A829L523 |
Locus tag | H5C78_RS22235 | Protein ID | WP_000170738.1 |
Coordinates | 4620945..4621052 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 4621101..4621167 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
H5C78_RS22205 | 4616831..4617022 | + | 192 | WP_000988308.1 | cellulose biosynthesis protein BcsF | - |
H5C78_RS22210 | 4617019..4618698 | + | 1680 | WP_001562264.1 | cellulose biosynthesis protein BcsG | - |
H5C78_RS22215 | 4618813..4619271 | - | 459 | WP_000526135.1 | IS200/IS605 family transposase | - |
H5C78_RS22220 | 4619496..4619603 | - | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
H5C78_RS22225 | 4619979..4620086 | - | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
H5C78_RS22230 | 4620462..4620569 | - | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
H5C78_RS22235 | 4620945..4621052 | - | 108 | WP_000170738.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- | 4621101..4621167 | + | 67 | - | - | Antitoxin |
H5C78_RS22240 | 4621528..4622799 | + | 1272 | WP_001318103.1 | amino acid permease | - |
H5C78_RS22245 | 4622829..4623833 | - | 1005 | WP_000107036.1 | dipeptide ABC transporter ATP-binding subunit DppF | - |
H5C78_RS22250 | 4623830..4624813 | - | 984 | WP_001196486.1 | dipeptide ABC transporter ATP-binding protein | - |
H5C78_RS22255 | 4624824..4625726 | - | 903 | WP_000084677.1 | dipeptide ABC transporter permease DppC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 4618813..4619271 | 458 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3864.67 Da Isoelectric Point: 9.0157
>T169414 WP_000170738.1 NZ_CP059917:c4621052-4620945 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASLIVNWLNKRK
MTLAELGMAFWHDLAAPVIAGILASLIVNWLNKRK
Download Length: 108 bp
>T169414 NZ_CP076470:3654711-3654962 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA
Antitoxin
Download Length: 67 bp
>AT169414 NZ_CP059917:4621101-4621167 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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