Detailed information of TA system TA169337

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 942861..943083
• Replicon: chromosome
• Accession: NZ_CP059907
• Organism: Escherichia coli strain 181.1

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: H5C80_RS04605
• Protein ID: WP_001295224.1
• Coordinates: 942976..943083 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	942861..942919 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H5C80_RS04580	938746..939750	+	1005	WP_000107036.1	dipeptide ABC transporter ATP-binding subunit DppF	-
H5C80_RS04585	939780..941051	-	1272	WP_001318103.1	amino acid permease	-
H5C80_RS04590	941527..941634	+	108	WP_000170738.1	type I toxin-antitoxin system toxin Ldr family protein	-
H5C80_RS04595	942010..942117	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
H5C80_RS04600	942493..942600	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	942861..942919	-	59	-	-	Antitoxin
H5C80_RS04605	942976..943083	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
H5C80_RS04610	943170..944849	-	1680	WP_001562264.1	cellulose biosynthesis protein BcsG	-
H5C80_RS04615	944846..945037	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
H5C80_RS04620	945034..946605	-	1572	WP_001204944.1	cellulose biosynthesis protein BcsE	-
H5C80_RS04625	946878..947066	+	189	WP_001063315.1	YhjR family protein	-
H5C80_RS04630	947078..947830	+	753	WP_000279544.1	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T169337 WP_001295224.1 NZ_CP059907:942976-943083 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T169337 NZ_CP076404:c4528286-4527945 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCATGTCACCGTCGGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CTGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGAGGAGAGCGAA
CTGATGCAGTCGCTACGCCAGGTGTGCAAACTGTCGGCGCGTAAACAAAAGCAGGTGCAGGCGTTTATTGGAGTGATTGC
CGGTAAACAGAAAGTCGCGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT169337 NZ_CP059907:c942919-942861 [Escherichia coli]
TCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin