Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 3797510..3798012 Replicon chromosome
Accession NZ_CP059467
Organism Aromatoleum bremense strain PbN1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag pbN1_RS17945 Protein ID WP_169119260.1
Coordinates 3797510..3797776 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag pbN1_RS17950 Protein ID WP_169202893.1
Coordinates 3797770..3798012 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
pbN1_RS17915 (pbN1_36420) 3792961..3793575 - 615 WP_169202897.1 hypothetical protein -
pbN1_RS17920 (pbN1_36430) 3793668..3794000 - 333 WP_169202896.1 cupin domain-containing protein -
pbN1_RS17925 (pbN1_36440) 3794009..3794761 - 753 WP_169202895.1 SDR family oxidoreductase -
pbN1_RS17930 (pbN1_36460) 3795058..3796215 + 1158 WP_169202894.1 PQQ-dependent sugar dehydrogenase -
pbN1_RS17935 (pbN1_36470) 3796300..3796659 + 360 WP_041646544.1 MbcA/ParS/Xre antitoxin family protein -
pbN1_RS17940 (pbN1_36480) 3796656..3797408 + 753 WP_210147571.1 RES family NAD+ phosphorylase -
pbN1_RS17945 (pbN1_36490) 3797510..3797776 - 267 WP_169119260.1 Txe/YoeB family addiction module toxin Toxin
pbN1_RS17950 (pbN1_36500) 3797770..3798012 - 243 WP_169202893.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
pbN1_RS17955 (pbN1_36510) 3798163..3798459 - 297 WP_169202892.1 hypothetical protein -
pbN1_RS17960 3798515..3798880 - 366 WP_169202891.1 hypothetical protein -
pbN1_RS17965 (pbN1_36520) 3798957..3799358 - 402 WP_169202890.1 hypothetical protein -
pbN1_RS17970 (pbN1_36530) 3799355..3799684 - 330 WP_169202889.1 hypothetical protein -
pbN1_RS21010 3799788..3799919 - 132 WP_280516165.1 hypothetical protein -
pbN1_RS17975 (pbN1_36540) 3800146..3801091 - 946 Protein_3533 IS5 family transposase -
pbN1_RS17980 3801151..3801669 - 519 WP_210147572.1 SHOCT domain-containing protein -
pbN1_RS17985 (pbN1_36550) 3801681..3802091 - 411 WP_169202887.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3800075..3801091 1016


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(27-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10093.76 Da        Isoelectric Point: 10.0262

>T168872 WP_169119260.1 NZ_CP059467:c3797776-3797510 [Aromatoleum bremense]
VVSWEIVYARQALKDAKKLAASGLKPKAQEVLVVLADDPFKNPPPFEKLVGDLAGAYSRRINIQHRIVYEVFANEKTVRV
LRMWTHYE

Download         Length: 267 bp

>T168872 NZ_CP076250:377911-378063 [Xanthomonas translucens pv. poae]
ATGAAGCGACTGTTCACCTTGATGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
TGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8888.23 Da        Isoelectric Point: 5.8020

>AT168872 WP_169202893.1 NZ_CP059467:c3798012-3797770 [Aromatoleum bremense]
MNTLTASEARANLYRLIDQTVESHEPIIITGKRNSAVLLSTEDWSAIQETLYLLAVPGMRESIKAGMAEPLAKSSKELKW

Download         Length: 243 bp

>AT168872 NZ_CP076250:378162-378296 [Xanthomonas translucens pv. poae]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTTTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References