Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
| Location | 1795345..1795527 | Replicon | chromosome |
| Accession | NZ_CP059180 | ||
| Organism | Staphylococcus aureus strain SH1000 | ||
Toxin (Protein)
| Gene name | sprA1 | Uniprot ID | - |
| Locus tag | SAURSH1000_RS08595 | Protein ID | WP_001801861.1 |
| Coordinates | 1795345..1795440 (+) | Length | 32 a.a. |
Antitoxin (RNA)
| Gene name | sprA1AS | ||
| Locus tag | - | ||
| Coordinates | 1795468..1795527 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAURSH1000_RS08555 (SAURSH1000_001709) | 1791005..1791631 | + | 627 | WP_000669046.1 | hypothetical protein | - |
| SAURSH1000_RS08560 (SAURSH1000_001710) | 1791672..1792016 | + | 345 | WP_000627551.1 | DUF3969 family protein | - |
| SAURSH1000_RS08565 (SAURSH1000_001711) | 1792114..1792665 | + | 552 | WP_000414205.1 | hypothetical protein | - |
| SAURSH1000_RS08570 (SAURSH1000_001712) | 1792883..1793524 | - | 642 | WP_000494956.1 | ImmA/IrrE family metallo-endopeptidase | - |
| SAURSH1000_RS08575 (SAURSH1000_001713) | 1793638..1793823 | - | 186 | WP_000809857.1 | hypothetical protein | - |
| SAURSH1000_RS08580 (SAURSH1000_001714) | 1793825..1794001 | - | 177 | WP_000375476.1 | hypothetical protein | - |
| SAURSH1000_RS08585 (SAURSH1000_001715) | 1794012..1794395 | - | 384 | WP_000070812.1 | hypothetical protein | - |
| SAURSH1000_RS08590 (SAURSH1000_001716) | 1794999..1795142 | - | 144 | WP_001549059.1 | transposase | - |
| SAURSH1000_RS08595 (SAURSH1000_001717) | 1795345..1795440 | + | 96 | WP_001801861.1 | type I toxin-antitoxin system Fst family toxin PepA1 | Toxin |
| - | 1795468..1795527 | - | 60 | - | - | Antitoxin |
| SAURSH1000_RS08600 (SAURSH1000_001718) | 1795563..1795664 | + | 102 | WP_001791893.1 | hypothetical protein | - |
| SAURSH1000_RS08605 (SAURSH1000_001719) | 1795642..1795818 | - | 177 | Protein_1692 | transposase | - |
| SAURSH1000_RS08610 (SAURSH1000_001720) | 1796012..1796389 | - | 378 | WP_001037045.1 | DUF1433 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3554.32 Da Isoelectric Point: 10.4449
>T168415 WP_001801861.1 NZ_CP059180:1795345-1795440 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
Download Length: 96 bp
>T168415 NZ_CP075878:1954125-1954466 [Listeria monocytogenes]
ATGGTAAAGCAAGGCGATATTATCAAGATCAATCTAAATCCAAAACAGGGACACGAGCAGCAAGGCTATCGGCCCTATAT
TTGCCTCAGTCATCATCTGGTAAGTGATTATGCAAATATCGCGATCTTTGCCCCAATCAGTAATACACCGCGCACCTATC
CGTTATATGTGCCTTTGACAGGGACAACCACAACCGGAAAAGTATTGCTGGATCAACTAGTTACGATCGATTACAACGCT
CGTAAGCATCAATACGTGGAAACTGTTTCGGATCCATTGCTCACAAAGCTATTAGATACAGTAAAAGTTATTTTTCAAAA
GAACGAGAGATCAACCAACTAA
ATGGTAAAGCAAGGCGATATTATCAAGATCAATCTAAATCCAAAACAGGGACACGAGCAGCAAGGCTATCGGCCCTATAT
TTGCCTCAGTCATCATCTGGTAAGTGATTATGCAAATATCGCGATCTTTGCCCCAATCAGTAATACACCGCGCACCTATC
CGTTATATGTGCCTTTGACAGGGACAACCACAACCGGAAAAGTATTGCTGGATCAACTAGTTACGATCGATTACAACGCT
CGTAAGCATCAATACGTGGAAACTGTTTCGGATCCATTGCTCACAAAGCTATTAGATACAGTAAAAGTTATTTTTCAAAA
GAACGAGAGATCAACCAACTAA
Antitoxin
Download Length: 60 bp
>AT168415 NZ_CP059180:c1795527-1795468 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
