Detailed information of TA system TA168402

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2259037..2259253
• Replicon: chromosome
• Accession: NZ_CP059156
• Organism: Staphylococcus aureus strain WKZ-1

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: HTZ90_RS11210
• Protein ID: WP_073392962.1
• Coordinates: 2259149..2259253 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2259037..2259092 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HTZ90_RS11190	2254130..2254450	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
HTZ90_RS11195	2254452..2255432	+	981	WP_180821688.1	CDF family zinc efflux transporter CzrB	-
HTZ90_RS11200	2255698..2256789	+	1092	WP_000495684.1	hypothetical protein	-
HTZ90_RS11205	2257077..2258723	+	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
-	2259037..2259092	+	56	-	-	Antitoxin
HTZ90_RS11210	2259149..2259253	-	105	WP_073392962.1	hypothetical protein	Toxin
HTZ90_RS11215	2259933..2260091	+	159	WP_001792784.1	hypothetical protein	-
HTZ90_RS11220	2260750..2261607	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
HTZ90_RS11225	2261675..2262457	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2257077..2258723	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T168402 WP_073392962.1 NZ_CP059156:c2259253-2259149 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T168402 NZ_CP075852:c3362375-3361911 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT168402 NZ_CP059156:2259037-2259092 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin