Detailed information of TA system TA168393

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1910980..1911160
• Replicon: chromosome
• Accession: NZ_CP059156
• Organism: Staphylococcus aureus strain WKZ-1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HTZ90_RS09150
• Protein ID: WP_001801861.1
• Coordinates: 1910980..1911075 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1911103..1911160 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HTZ90_RS09120	1906124..1906750	+	627	WP_000669038.1	hypothetical protein	-
HTZ90_RS09125	1906791..1907135	+	345	WP_000627550.1	DUF3969 family protein	-
HTZ90_RS09130	1907233..1907805	+	573	WP_000414222.1	hypothetical protein	-
HTZ90_RS09135	1907954..1909321	-	1368	WP_001093574.1	FRG domain-containing protein	-
HTZ90_RS09140	1909321..1909890	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
HTZ90_RS09145	1910083..1910529	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
HTZ90_RS09150	1910980..1911075	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1911103..1911160	-	58	-	-	Antitoxin
HTZ90_RS09155	1911198..1911299	+	102	WP_001791232.1	hypothetical protein	-
HTZ90_RS09160	1911474..1911917	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
HTZ90_RS09165	1911917..1912360	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
HTZ90_RS09170	1912360..1912802	-	443	Protein_1807	DUF1433 domain-containing protein	-
HTZ90_RS09175	1913327..1915747	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T168393 WP_001801861.1 NZ_CP059156:1910980-1911075 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T168393 NZ_CP075852:1429870-1430088 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT168393 NZ_CP059156:c1911160-1911103 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin