Detailed information of TA system TA168373

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1935229..1935409
• Replicon: chromosome
• Accession: NZ_CP059155
• Organism: Staphylococcus aureus strain WKZ-2

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HTZ91_RS09265
• Protein ID: WP_001801861.1
• Coordinates: 1935229..1935324 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1935352..1935409 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HTZ91_RS09235	1930373..1930999	+	627	WP_000669038.1	hypothetical protein	-
HTZ91_RS09240	1931040..1931384	+	345	WP_000627550.1	DUF3969 family protein	-
HTZ91_RS09245	1931482..1932054	+	573	WP_000414222.1	hypothetical protein	-
HTZ91_RS09250	1932203..1933570	-	1368	WP_001093574.1	FRG domain-containing protein	-
HTZ91_RS09255	1933570..1934139	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
HTZ91_RS09260	1934332..1934778	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
HTZ91_RS09265	1935229..1935324	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1935352..1935409	-	58	-	-	Antitoxin
HTZ91_RS09270	1935447..1935548	+	102	WP_001791232.1	hypothetical protein	-
HTZ91_RS09275	1935723..1936166	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
HTZ91_RS09280	1936166..1936609	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
HTZ91_RS09285	1936609..1937051	-	443	Protein_1830	DUF1433 domain-containing protein	-
HTZ91_RS09290	1937576..1939996	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hysA / selk	1910418..1993095	82677

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T168373 WP_001801861.1 NZ_CP059155:1935229-1935324 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T168373 NZ_CP075737:c2284206-2283910 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT168373 NZ_CP059155:c1935409-1935352 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin