Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 818821..819628 Replicon chromosome
Accession NZ_CP059068
Organism Rhodoferax sp. AJA081-3

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag HZ993_RS03810 Protein ID WP_209395946.1
Coordinates 818821..819306 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag HZ993_RS03815 Protein ID WP_209395947.1
Coordinates 819299..819628 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZ993_RS03790 (HZ993_03795) 815380..816033 + 654 WP_209395943.1 uracil phosphoribosyltransferase -
HZ993_RS03795 (HZ993_03800) 816098..817090 + 993 WP_209395944.1 nucleotidyltransferase domain-containing protein -
HZ993_RS03800 (HZ993_03805) 817157..818509 + 1353 WP_209395945.1 amidohydrolase family protein -
HZ993_RS03805 (HZ993_03810) 818592..818762 + 171 WP_245213811.1 hypothetical protein -
HZ993_RS03810 (HZ993_03815) 818821..819306 - 486 WP_209395946.1 type II toxin-antitoxin system YhaV family toxin Toxin
HZ993_RS03815 (HZ993_03820) 819299..819628 - 330 WP_209395947.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
HZ993_RS03820 (HZ993_03825) 820346..822049 + 1704 WP_245213812.1 zinc-ribbon domain-containing protein -
HZ993_RS03825 (HZ993_03830) 822458..822934 - 477 WP_209395949.1 peptidylprolyl isomerase -
HZ993_RS03830 (HZ993_03835) 823001..824464 - 1464 WP_209395950.1 exodeoxyribonuclease I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(21-157)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 18779.46 Da        Isoelectric Point: 10.2036

>T168202 WP_209395946.1 NZ_CP059068:c819306-818821 [Rhodoferax sp. AJA081-3]
MSERKKPSSPSARWVVNGWSVFAHPLFLAQLQTLTLQVETLKTKDPQGYIKKNATKRLAAIQKLAFEVIPQDPTRVEYRQ
GGTLGDEYKHWFRAKFFQQYRLFFRYHLQAKIIVLAWVNDDDTKRAYDSSDDAYRVFRKMLESGHPPDDWDALLAQAKAS
K

Download         Length: 486 bp

>T168202 NZ_CP075654:34679-34984 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTTCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCCCGCCTGCTGTCAGACAAAGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGTCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11877.29 Da        Isoelectric Point: 4.2767

>AT168202 WP_209395947.1 NZ_CP059068:c819628-819299 [Rhodoferax sp. AJA081-3]
MPTTMEVESTLTERYQTTVPASVRSALRLGKRDKIHYSIRPGGEVVLSRAADVEADDPAMGAFLGFLAHDMTQHPEHLQA
VDADLVERIQALTAGVELDMDASLSPDDE

Download         Length: 330 bp

>AT168202 NZ_CP075654:34459-34677 [Escherichia coli]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAATTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGTTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGATGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References