Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 274006..274228 Replicon chromosome
Accession NZ_CP058874
Organism Escherichia coli strain STLEFF_47

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag HZT32_RS01325 Protein ID WP_001295224.1
Coordinates 274121..274228 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 274006..274072 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT32_RS01305 269447..270349 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
HZT32_RS01310 270360..271343 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
HZT32_RS01315 271340..272344 + 1005 WP_240724426.1 dipeptide ABC transporter ATP-binding subunit DppF -
HZT32_RS01320 272374..273645 - 1272 WP_001318103.1 aromatic amino acid transport family protein -
- 274006..274072 - 67 - - Antitoxin
HZT32_RS01325 274121..274228 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
HZT32_RS01330 274604..274711 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
HZT32_RS01335 274798..276477 - 1680 WP_001562264.1 cellulose biosynthesis protein BcsG -
HZT32_RS01340 276474..276665 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
HZT32_RS01345 276662..278233 - 1572 WP_001204944.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
HZT32_RS01350 278506..278694 + 189 WP_001063315.1 cellulose biosynthesis protein BcsR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T167843 WP_001295224.1 NZ_CP058874:274121-274228 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T167843 NZ_CP075472:2567119-2567226 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT167843 NZ_CP058874:c274072-274006 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References