167308

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1350318..1350801 Replicon chromosome
Accession NZ_CP058742
Organism Streptococcus suis strain 10

Toxin (Protein)


Gene name relE Uniprot ID D5AIX4
Locus tag SSU10_RS06575 Protein ID WP_012027435.1
Coordinates 1350318..1350578 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0Z8BIX7
Locus tag SSU10_RS06580 Protein ID WP_012775256.1
Coordinates 1350580..1350801 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 1355569..1356771 1202


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10273.79 Da        Isoelectric Point: 9.3944

>T167308 WP_012027435.1 NZ_CP058742:c1350578-1350318 [Streptococcus suis]
MYHLEYSKKAQKQIMKLDRQIQRLLFAWIDKHLEGTDNPRANGKGLTGNHANEWRYRIGDYRLICDIQDDKLVILALEFG
HRKDVY

Download         Length: 261 bp

>T167308 NZ_CP075112:c4086987-4086643 [Salmonella enterica subsp. enterica serovar Corvallis]
ATGCAAAACGTTTTATCACTGTCTTCACCGGCAGCGACCCCGTCACGCTTGTCGCCCGTCGAAGCCTGGCGAAAACTGCT
GTCGTATTTACTGCAACGCCACTACGGCCTGGAACTCAACGACACGCCATTCTGCGACGATAGTGTTATTCAGGAACATA
TCAACGCAGGCGTTACGCTTGCCGATGCCGTGAACTTTCTGGTGGAAAAGTACGAACTTGTTCGTATCGATCGCAAGGGA
TTTAGCTGGCAGGAACAATCACCCTATCTTCGAGCTGTAGACATTCTGCGGGCGCGACAGGCTACGGGTCTGTTGCGACG
TCAACGCTATCTCGCGGCACACTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8566.55 Da        Isoelectric Point: 4.4791

>AT167308 WP_012775256.1 NZ_CP058742:c1350801-1350580 [Streptococcus suis]
MSTVTIRLNQEEEVFFKSYAQLTGQSLSSLFKKALERDIEDEYDLKIYHQAYDEYKADPETISHADFKKELGL

Download         Length: 222 bp

>AT167308 NZ_CP075112:c4087331-4087002 [Salmonella enterica subsp. enterica serovar Corvallis]
ATGCCCCAAAACCAACCCTCCGTGCCTGTCTGGGGCCTGCGGAGCGATATCACGCCCTCGTTTGGCGCGCGGTTAGTGCA
GGAAGGCTGTCGCCTGCACTTTCTGGCTGACCGCGCCAGCCTTTGCGGTAATTTCACGCCGGAGCAACTGCAAACACTGG
AGGTCACCTTTCCGCAGTTCGTGAAACAACTGGAATCGGTGCTAAAAAGCGGGGCGCTCGATCCGCGCCAGCCGCACCGC
CACAGCATCACCCTCAATGGCCTGACCTGCGAGGCCGACACCAACGGTAGCCACGGCTACGTTTACCTCACTATCTACCC
AGCCGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K1T1M7

Antitoxin

Source ID Structure
AlphaFold DB A0A0Z8BIX7

References