166989

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 5300745..5301352 Replicon chromosome
Accession NZ_CP058644
Organism Pseudomonas yamanorum strain GZD14026

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HZF02_RS24445 Protein ID WP_179447811.1
Coordinates 5300745..5301059 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HZF02_RS24450 Protein ID WP_124369841.1
Coordinates 5301059..5301352 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZF02_RS24430 5296825..5298726 - 1902 WP_179447808.1 potassium transporter Kup -
HZF02_RS24435 5299310..5300221 + 912 WP_179447809.1 DUF3800 domain-containing protein -
HZF02_RS24440 5300534..5300755 - 222 WP_179447810.1 hypothetical protein -
HZF02_RS24445 5300745..5301059 + 315 WP_179447811.1 hypothetical protein Toxin
HZF02_RS24450 5301059..5301352 + 294 WP_124369841.1 helix-turn-helix domain-containing protein Antitoxin
HZF02_RS24455 5301397..5302512 - 1116 WP_179447812.1 acyltransferase -
HZF02_RS24460 5302605..5303576 - 972 WP_179447813.1 hypothetical protein -
HZF02_RS24465 5303549..5304253 - 705 WP_179447814.1 hypothetical protein -
HZF02_RS24470 5304250..5304795 - 546 WP_179447815.1 DNA-binding protein -
HZF02_RS24475 5304792..5305721 - 930 WP_179447816.1 hypothetical protein -
HZF02_RS24480 5305711..5306214 - 504 WP_179447817.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-72)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11791.49 Da        Isoelectric Point: 8.3906

>T166989 WP_179447811.1 NZ_CP058644:5300745-5301059 [Pseudomonas yamanorum]
MIFIESPIFTEDLGELLSDESYREFQEYLAENPTAGDVIQGTNGLRKVRWSANGKGKSGGVRVIYFHLSAAYQIRLILIY
RKGIKDDLSPAEKKVLAELNRGWK

Download         Length: 315 bp

>T166989 NZ_CP074580:c310555-309233 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCGGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGAGAGCAGATGTTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11001.59 Da        Isoelectric Point: 10.1711

>AT166989 WP_124369841.1 NZ_CP058644:5301059-5301352 [Pseudomonas yamanorum]
MEKNLFNRLVESMTQMDEIDRGERPPSREFHVDAVKVKMIRKATGLSQARFAKAIDVAVGTLQNWEQGRREPEGPARALL
RAIHNDPGHVLAALEQR

Download         Length: 294 bp

>AT166989 NZ_CP074580:c310821-310555 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGATGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References