Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1491562..1492061 Replicon chromosome
Accession NZ_CP058638
Organism Rhodococcus sp. ZPP

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HYG77_RS07010 Protein ID WP_109328189.1
Coordinates 1491807..1492061 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HYG77_RS07005 Protein ID WP_208962257.1
Coordinates 1491562..1491810 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYG77_RS06990 (HYG77_06980) 1487223..1488701 + 1479 WP_208962255.1 NAD(P)/FAD-dependent oxidoreductase -
HYG77_RS06995 (HYG77_06985) 1488682..1489830 - 1149 WP_109328196.1 acyl-CoA dehydrogenase family protein -
HYG77_RS07000 (HYG77_06990) 1489842..1491023 - 1182 WP_208962256.1 thiolase family protein -
HYG77_RS07005 (HYG77_06995) 1491562..1491810 + 249 WP_208962257.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HYG77_RS07010 (HYG77_07000) 1491807..1492061 + 255 WP_109328189.1 Txe/YoeB family addiction module toxin Toxin
HYG77_RS07015 (HYG77_07005) 1492762..1493034 + 273 WP_208962258.1 hypothetical protein -
HYG77_RS39470 1493926..1494111 + 186 Protein_1403 RNA polymerase subunit sigma -
HYG77_RS07020 (HYG77_07010) 1494095..1495285 + 1191 WP_208962259.1 anti-sigma-D factor RsdA -
HYG77_RS07025 (HYG77_07015) 1495519..1495866 - 348 WP_109328183.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10068.31 Da        Isoelectric Point: 7.4659

>T166980 WP_109328189.1 NZ_CP058638:1491807-1492061 [Rhodococcus sp. ZPP]
VNTASTDDGWEDYTHWSITDRKILKKINDLIKDIKRSPYEGIGKPERLRHIDDNVWSRRITQEHRLVYVIVDDTVVIQQA
RHHY

Download         Length: 255 bp

>T166980 NZ_CP058638:1491807-1492061 [Rhodococcus sp. ZPP]
GTGAACACCGCCTCCACCGACGACGGGTGGGAGGACTACACCCACTGGTCGATCACCGACCGCAAAATTCTGAAGAAGAT
CAACGACCTGATCAAAGACATCAAGCGGTCACCCTACGAAGGCATCGGGAAGCCCGAACGCCTCCGCCACATCGACGACA
ACGTCTGGTCCCGGCGCATCACCCAGGAACACCGGTTGGTGTACGTGATCGTCGACGACACAGTCGTCATCCAGCAAGCC
CGCCACCACTACTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9221.39 Da        Isoelectric Point: 5.8315

>AT166980 WP_208962257.1 NZ_CP058638:1491562-1491810 [Rhodococcus sp. ZPP]
MTAITATEARKNLFGLVSQVNKDHTTVEIVSKNGNAVLLSKDDYDSIMETAYLLSSPANARRLFRSLEATRRGEYTEREL
IE

Download         Length: 249 bp

>AT166980 NZ_CP058638:1491562-1491810 [Rhodococcus sp. ZPP]
ATGACTGCAATAACAGCCACCGAGGCCAGGAAGAACCTGTTCGGCTTGGTCAGCCAAGTGAACAAGGACCACACAACCGT
GGAAATAGTCTCCAAGAACGGGAACGCTGTTCTTCTCTCGAAGGACGACTACGACTCCATCATGGAAACGGCCTACCTGC
TGTCCAGCCCGGCGAACGCTCGCCGCCTGTTTCGCAGTCTGGAGGCAACCCGGCGCGGTGAATACACCGAAAGGGAACTG
ATCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References