Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4333056..4333314 Replicon chromosome
Accession NZ_CP058596
Organism Escherichia coli strain UPEC_U013

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag HYE75_RS20860 Protein ID WP_001181672.1
Coordinates 4333105..4333314 (+) Length 70 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4333056..4333113 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYE75_RS20845 4328885..4330144 - 1260 WP_000494928.1 hypothetical protein -
HYE75_RS20850 4330273..4331766 - 1494 WP_001443162.1 sulfatase-like hydrolase/transferase -
HYE75_RS20855 4331786..4332547 - 762 WP_001274832.1 hypothetical protein -
- 4333056..4333113 - 58 - - Antitoxin
HYE75_RS20860 4333105..4333314 + 210 WP_001181672.1 type I toxin-antitoxin system Hok family toxin Toxin
HYE75_RS20865 4333419..4334549 - 1131 WP_001118464.1 molecular chaperone DnaJ -
HYE75_RS20870 4334638..4336554 - 1917 WP_000516135.1 molecular chaperone DnaK -
HYE75_RS20875 4336926..4337330 + 405 WP_000843687.1 DUF2541 family protein -
HYE75_RS20880 4337356..4338069 + 714 WP_001102391.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(25-66)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 7757.25 Da        Isoelectric Point: 9.3680

>T166897 WP_001181672.1 NZ_CP058596:4333105-4333314 [Escherichia coli]
MQNTCRVPLTDRKVKEKRAMKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 210 bp

>T166897 NZ_CP074541:2126012-2126114 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 58 bp

>AT166897 NZ_CP058596:c4333113-4333056 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References