Detailed information of TA system TA166739

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 2109732..2110240
• Replicon: chromosome
• Accession: NZ_CP058364
• Organism: Galbibacter sp. BG1

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: HX109_RS09375
• Protein ID: WP_178951382.1
• Coordinates: 2109980..2110240 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: HX109_RS09370
• Protein ID: WP_178951381.1
• Coordinates: 2109732..2109980 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HX109_RS09360	2106294..2106821	+	528	WP_178951379.1	inorganic diphosphatase	-
HX109_RS09365	2107024..2109381	+	2358	WP_178951380.1	sodium-translocating pyrophosphatase	-
HX109_RS09370	2109732..2109980	+	249	WP_178951381.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HX109_RS09375	2109980..2110240	+	261	WP_178951382.1	Txe/YoeB family addiction module toxin	Toxin
HX109_RS09380	2110286..2110900	-	615	WP_178951383.1	deoxynucleoside kinase	-
HX109_RS09385	2111300..2112556	+	1257	WP_178951384.1	methionine adenosyltransferase	-
HX109_RS09390	2112888..2114168	+	1281	WP_178951385.1	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10356.02 Da
• Isoelectric Point: 10.1790

>T166739 WP_178951382.1 NZ_CP058364:2109980-2110240 [Galbibacter sp. BG1]
MKLIWSITAWNDYLYWQKVDRKTVKRINELVKSCIRTPFEGIGKPEALKGDLQGYWSRRITSEHRLVYKFTNESLWIAAC
RYHYGK

Nucleotide

• Length: 261 bp

>T166739 NZ_CP074415:2205971-2206267 [Vibrio parahaemolyticus]
ATGCAAAAGAATAAATATAAGCTAAGTAAATTAGCACAGACTCATTTACAAAAAATCAGAAACTATACCGTCAACAATTT
CTCTGAGATGCAATGGCGAAGCTACAAAGATACCTTACTAACAGGGTTTCAAATGCTTGCTGACAACCCGGCTGTTGGTC
GCAGTTGCGATGAGATATACCCAAGTGGTTTTTATTTCCCTGTAGGCAAGCACACCGCTTACTTTACAAAAGAAGATGGC
TTCATTTTAGTTGTTGCTGTACTCGGTCAATCACAACTTCCGCAGAACCACCTGTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9387.67 Da
• Isoelectric Point: 4.6437

>AT166739 WP_178951381.1 NZ_CP058364:2109732-2109980 [Galbibacter sp. BG1]
MEVVNYTDFRSNLKHWFDKVINDVSDIVIKRKGGKDLVLISLDEYNSLKETTYLLTGKNRDVLLNSIKELEAGDGIEKDL
AE

Nucleotide

• Length: 249 bp

>AT166739 NZ_CP074415:2205722-2205964 [Vibrio parahaemolyticus]
ATGCACACATTAACAGCAAATGATGCCAAACGTAATTTTGGTGAGTTACTTCTGAGCGCTCAACGTGAGCCAGTGAAAAT
TAGCAAAAATAGCAAAGATGCCGTAGTTGTTATGTCGATTAAAGACTATGAAGAGCTGGAGGCAATGAAAACTGATTACC
TGAGACATTGTTTCGAGTCAGCGAAGCAAGACTTGGCACAAGGCAATGTAGTTAATGGTGAAGACTTTTTAAACGCCTTA
TAA