Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 778208..778773 | Replicon | chromosome |
Accession | NZ_CP058349 | ||
Organism | Pseudomonas sp. ABC1 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | HW090_RS03305 | Protein ID | WP_179112141.1 |
Coordinates | 778495..778773 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | HW090_RS03300 | Protein ID | WP_179112140.1 |
Coordinates | 778208..778495 (-) | Length | 96 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HW090_RS03275 | 773759..775039 | - | 1281 | WP_179112136.1 | hypothetical protein | - |
HW090_RS03280 | 775497..775883 | - | 387 | WP_179112137.1 | hypothetical protein | - |
HW090_RS03285 | 775876..776124 | - | 249 | WP_179112138.1 | hypothetical protein | - |
HW090_RS03290 | 776117..776305 | - | 189 | WP_179114808.1 | helix-turn-helix domain-containing protein | - |
HW090_RS03295 | 776887..778161 | - | 1275 | WP_179112139.1 | hypothetical protein | - |
HW090_RS03300 | 778208..778495 | - | 288 | WP_179112140.1 | HigA family addiction module antidote protein | Antitoxin |
HW090_RS03305 | 778495..778773 | - | 279 | WP_179112141.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HW090_RS03310 | 779058..779249 | - | 192 | Protein_655 | tyrosine-type recombinase/integrase | - |
HW090_RS03315 | 779272..779979 | - | 708 | WP_179112142.1 | AAA family ATPase | - |
HW090_RS03320 | 780049..780477 | - | 429 | WP_179112143.1 | hypothetical protein | - |
HW090_RS03325 | 780474..781249 | - | 776 | Protein_658 | ATP-binding protein | - |
HW090_RS03330 | 781246..782139 | - | 894 | WP_179112144.1 | phage replication protein | - |
HW090_RS03335 | 782139..782360 | - | 222 | WP_179112145.1 | hypothetical protein | - |
HW090_RS03340 | 782357..782590 | - | 234 | WP_179112146.1 | hypothetical protein | - |
HW090_RS03345 | 782580..782996 | - | 417 | WP_179112147.1 | hypothetical protein | - |
HW090_RS03350 | 782993..783427 | - | 435 | WP_179112148.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 772160..792150 | 19990 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10673.25 Da Isoelectric Point: 9.5915
>T166637 WP_179112141.1 NZ_CP058349:c778773-778495 [Pseudomonas sp. ABC1]
MIKSFQHKGLRKLFETGSTAGVQPSHAKRLRMQLAALDTAMTVDDMDIPGFRLHPLKGEMRGRWSIMVNGNWRLTFEFRD
GNAYVLDYEDYH
MIKSFQHKGLRKLFETGSTAGVQPSHAKRLRMQLAALDTAMTVDDMDIPGFRLHPLKGEMRGRWSIMVNGNWRLTFEFRD
GNAYVLDYEDYH
Download Length: 279 bp
>T166637 NZ_CP074364:278529-278663 [Xanthomonas translucens pv. cerealis]
ATGAAGCGTACTTTTGCGTGGATGCTGCTGGCGATGTTTTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA
ATGAAGCGTACTTTTGCGTGGATGCTGCTGGCGATGTTTTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10655.19 Da Isoelectric Point: 7.3184
>AT166637 WP_179112140.1 NZ_CP058349:c778495-778208 [Pseudomonas sp. ABC1]
MNMHNPPHPGEFITDIYLEPNGISGRELAEKLRVAPSTLSRVLKGTSRVTPEMALRLSVALGRSPESWLAMQDTYDLWNA
RQHVDLQQVGRLAFA
MNMHNPPHPGEFITDIYLEPNGISGRELAEKLRVAPSTLSRVLKGTSRVTPEMALRLSVALGRSPESWLAMQDTYDLWNA
RQHVDLQQVGRLAFA
Download Length: 288 bp
>AT166637 NZ_CP074364:278278-278430 [Xanthomonas translucens pv. cerealis]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
CGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
CGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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