Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4300221..4300479 Replicon chromosome
Accession NZ_CP057565
Organism Escherichia fergusonii strain RHB23-C01

Toxin (Protein)


Gene name hokA Uniprot ID -
Locus tag HVX91_RS20560 Protein ID WP_181202950.1
Coordinates 4300221..4300373 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokA
Locus tag -
Coordinates 4300424..4300479 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVX91_RS20535 4296086..4296796 - 711 WP_000190514.1 DUF3053 domain-containing protein -
HVX91_RS20540 4297234..4298604 + 1371 WP_181812031.1 MFS transporter -
HVX91_RS20545 4298854..4299144 + 291 WP_000455800.1 HTH-type transcriptional regulator -
HVX91_RS20550 4299426..4299638 + 213 WP_000014594.1 RNA chaperone/antiterminator CspA -
HVX91_RS20555 4299692..4300063 - 372 WP_072274202.1 membrane protein insertion efficiency factor YidD -
HVX91_RS20560 4300221..4300373 - 153 WP_181202950.1 type I toxin-antitoxin system toxin HokA Toxin
- 4300424..4300479 + 56 - - Antitoxin
HVX91_RS20565 4300674..4301033 - 360 WP_141095883.1 hypothetical protein -
HVX91_RS20570 4301102..4303171 - 2070 WP_181812032.1 glycine--tRNA ligase subunit beta -
HVX91_RS20575 4303181..4304092 - 912 WP_001168544.1 glycine--tRNA ligase subunit alpha -
HVX91_RS20580 4304188..4304487 - 300 WP_024256552.1 YsaB family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5926.17 Da        Isoelectric Point: 6.9160

>T165539 WP_181202950.1 NZ_CP057565:c4300373-4300221 [Escherichia fergusonii]
MPQKYGLLSLIVICFTLLFFTWMIRDSLCELHIKQENYELAAFLACKLKE

Download         Length: 153 bp

>T165539 NZ_CP073924:2741402-2741509 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 56 bp

>AT165539 NZ_CP057565:4300424-4300479 [Escherichia fergusonii]
GTTGAAGCATAGAGGCAGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References