Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3468347..3468605 Replicon chromosome
Accession NZ_CP057238
Organism Escherichia fergusonii strain RHB32-C09

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag HVZ00_RS16755 Protein ID WP_181668149.1
Coordinates 3468347..3468556 (-) Length 70 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3468548..3468605 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVZ00_RS16735 3463412..3463999 + 588 WP_002431696.1 molybdopterin adenylyltransferase -
HVZ00_RS16740 3464033..3464599 - 567 WP_000528529.1 acetate uptake transporter -
HVZ00_RS16745 3465107..3467023 + 1917 WP_000516135.1 molecular chaperone DnaK -
HVZ00_RS16750 3467112..3468242 + 1131 WP_001118464.1 molecular chaperone DnaJ -
HVZ00_RS16755 3468347..3468556 - 210 WP_181668149.1 type I toxin-antitoxin system Hok family toxin Toxin
- 3468548..3468605 + 58 - - Antitoxin
HVZ00_RS16760 3469040..3470206 + 1167 WP_046076806.1 Na+/H+ antiporter NhaA -
HVZ00_RS16765 3470274..3471173 + 900 WP_000019049.1 transcriptional activator NhaR -
HVZ00_RS16770 3471269..3471532 - 264 WP_001274021.1 30S ribosomal protein S20 -
HVZ00_RS16775 3471635..3471853 + 219 WP_046076805.1 DUF2575 family protein -
HVZ00_RS16780 3471861..3472802 + 942 WP_000767324.1 bifunctional riboflavin kinase/FAD synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(26-66)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 7752.30 Da        Isoelectric Point: 9.3680

>T165046 WP_181668149.1 NZ_CP057238:c3468556-3468347 [Escherichia fergusonii]
MLNTCRVPLTDRKVKEKRAMKQHKAIIVALIVICITAVVVALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 210 bp

>T165046 NZ_CP073665:c1714761-1714600 [Burkholderia contaminans]
GTGACCACGCTCTACATGCTCGATACGAGCATCTGTTCGTTCATCATGCGCGAGCGGCCGCCCGTGGTGCTGTCCCGGTT
GCAATCGTGCGTCAATGCGCAGCACCGGATCGTCGTCTCGGCAATTACCTATGCCGAAATGCGATTCGGCGCGGCCGGCT
AG

Antitoxin


Download         Length: 58 bp

>AT165046 NZ_CP057238:3468548-3468605 [Escherichia fergusonii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References