Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 983692..983938 Replicon chromosome
Accession NZ_CP057220
Organism Escherichia fergusonii strain RHB32-C22

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag HVZ07_RS04715 Protein ID WP_000956458.1
Coordinates 983786..983938 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 983692..983744 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVZ07_RS04700 979200..980999 + 1800 WP_000211943.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
HVZ07_RS04705 980999..982711 + 1713 WP_046083135.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
HVZ07_RS04710 982785..983519 + 735 WP_046083134.1 phosphoadenosine phosphosulfate reductase -
- 983692..983744 - 53 - - Antitoxin
HVZ07_RS04715 983786..983938 + 153 WP_000956458.1 type I toxin-antitoxin system Hok family toxin Toxin
HVZ07_RS04720 984174..986831 + 2658 WP_181668202.1 CRISPR-associated helicase Cas3' -
HVZ07_RS04725 986929..988491 + 1563 WP_181668203.1 type I-E CRISPR-associated protein Cse1/CasA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T164977 WP_000956458.1 NZ_CP057220:983786-983938 [Escherichia fergusonii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

>T164977 NZ_CP073624:1908412-1908666 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 53 bp

>AT164977 NZ_CP057220:c983744-983692 [Escherichia fergusonii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References