Detailed information of TA system TA164807

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symER/SymE(toxin)
• Location: 3877021..3877433
• Replicon: chromosome
• Accession: NZ_CP057104
• Organism: Escherichia fergusonii strain RHB38-C01

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: HVZ66_RS18825
• Protein ID: WP_181590840.1
• Coordinates: 3877092..3877433 (+)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	symR
Locus tag	-
Coordinates	3877021..3877097 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HVZ66_RS18815	3873869..3875458	+	1590	WP_181590838.1	type I restriction-modification system methyltransferase	-
HVZ66_RS18820	3875455..3876864	+	1410	WP_181590839.1	restriction endonuclease subunit S	-
-	3877021..3877097	-	77	NuclAT_10	-	Antitoxin
-	3877021..3877097	-	77	NuclAT_10	-	Antitoxin
-	3877021..3877097	-	77	NuclAT_10	-	Antitoxin
-	3877021..3877097	-	77	NuclAT_10	-	Antitoxin
-	3877021..3877097	-	77	NuclAT_11	-	Antitoxin
-	3877021..3877097	-	77	NuclAT_11	-	Antitoxin
-	3877021..3877097	-	77	NuclAT_11	-	Antitoxin
-	3877021..3877097	-	77	NuclAT_11	-	Antitoxin
HVZ66_RS18825	3877092..3877433	+	342	WP_181590840.1	endoribonuclease SymE	Toxin
HVZ66_RS18830	3877595..3878974	+	1380	WP_015953743.1	5-methylcytosine-specific restriction endonuclease subunit McrB	-
HVZ66_RS18835	3878974..3880020	+	1047	WP_072004067.1	5-methylcytosine-specific restriction endonuclease system specificity protein McrC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12336.16 Da
• Isoelectric Point: 8.4951

>T164807 WP_181590840.1 NZ_CP057104:3877092-3877433 [Escherichia fergusonii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVRDFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T164807 NZ_CP073310:32153-32440 [Enterobacter cloacae]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin

Nucleotide

• Length: 77 bp

>AT164807 NZ_CP057104:c3877097-3877021 [Escherichia fergusonii]
AGTCATAACTGCTATTCTCCTGGAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin