Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 2054424..2054649 | Replicon | chromosome |
Accession | NZ_CP055675 | ||
Organism | Escherichia fergusonii strain RHB28-C13 |
Toxin (Protein)
Gene name | hokW | Uniprot ID | A0A8E4IMY5 |
Locus tag | HVY52_RS09825 | Protein ID | WP_000813260.1 |
Coordinates | 2054494..2054649 (+) | Length | 52 a.a. |
Antitoxin (RNA)
Gene name | sokW | ||
Locus tag | - | ||
Coordinates | 2054424..2054482 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HVY52_RS09785 | 2049484..2049702 | - | 219 | WP_001171946.1 | hypothetical protein | - |
HVY52_RS09790 | 2049774..2050073 | - | 300 | WP_042046576.1 | hypothetical protein | - |
HVY52_RS09795 | 2050427..2050765 | - | 339 | WP_001397087.1 | peptidase S24-like family protein | - |
HVY52_RS09800 | 2051157..2051399 | + | 243 | WP_000747951.1 | hypothetical protein | - |
HVY52_RS09805 | 2051383..2051808 | + | 426 | WP_000693883.1 | Rha family transcriptional regulator | - |
HVY52_RS09810 | 2051880..2052950 | + | 1071 | WP_023154928.1 | phage replisome organizer protein | - |
HVY52_RS09815 | 2052991..2053416 | + | 426 | WP_021546098.1 | DUF977 family protein | - |
HVY52_RS09820 | 2053591..2054256 | + | 666 | WP_000150294.1 | epoxyqueuosine reductase QueH | - |
- | 2054424..2054482 | - | 59 | - | - | Antitoxin |
HVY52_RS09825 | 2054494..2054649 | + | 156 | WP_000813260.1 | type I toxin-antitoxin system toxin HokD | Toxin |
HVY52_RS09830 | 2054793..2055185 | + | 393 | WP_000737636.1 | hypothetical protein | - |
HVY52_RS09835 | 2055482..2055760 | + | 279 | WP_024175747.1 | hypothetical protein | - |
HVY52_RS09840 | 2055762..2056811 | + | 1050 | WP_048949148.1 | DUF968 domain-containing protein | - |
HVY52_RS09845 | 2056824..2057183 | + | 360 | WP_089585352.1 | RusA family crossover junction endodeoxyribonuclease | - |
HVY52_RS09850 | 2057180..2057869 | + | 690 | WP_181203391.1 | antiterminator | - |
HVY52_RS09875 | 2058666..2058881 | + | 216 | WP_000839572.1 | class II holin family protein | - |
HVY52_RS09880 | 2058886..2059236 | + | 351 | WP_001545374.1 | YdfR family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2037393..2091190 | 53797 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 52 a.a. Molecular weight: 5766.92 Da Isoelectric Point: 6.1531
>T162467 WP_000813260.1 NZ_CP055675:2054494-2054649 [Escherichia fergusonii]
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVTVFTAYEPEE
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVTVFTAYEPEE
Download Length: 156 bp
>T162467 NZ_CP071797:c2505289-2505020 [Pseudomonas fluorescens]
ATGCAGGTTGAGTGGCAGCCCGAAGCTCGGGCTGAACTCCTGCACATTCTTGACTACATCAGTGACCGGAATTTCAAAGC
GGCTAACAAGCTTTCAAACGCTATCGAAGCCGCCACGGTTACCCTTACCAAACATCCACACCTCTATCGAGTGGGGCGAA
CTCCCGGCACTCGTGAGATGGTCGTACATCCCAACTACCTGCTCATTTACCAAGCGGTGGGCCGGATAAATATTCTGGGC
GTTGTGCACGCACGTCAGGAATATCCGTGA
ATGCAGGTTGAGTGGCAGCCCGAAGCTCGGGCTGAACTCCTGCACATTCTTGACTACATCAGTGACCGGAATTTCAAAGC
GGCTAACAAGCTTTCAAACGCTATCGAAGCCGCCACGGTTACCCTTACCAAACATCCACACCTCTATCGAGTGGGGCGAA
CTCCCGGCACTCGTGAGATGGTCGTACATCCCAACTACCTGCTCATTTACCAAGCGGTGGGCCGGATAAATATTCTGGGC
GTTGTGCACGCACGTCAGGAATATCCGTGA
Antitoxin
Download Length: 59 bp
>AT162467 NZ_CP055675:c2054482-2054424 [Escherichia fergusonii]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTAGATTTGCCGTTCATAGATTGAGCCTCA
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTAGATTTGCCGTTCATAGATTGAGCCTCA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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