Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2221669..2222217 Replicon chromosome
Accession NZ_CP055265
Organism Agrobacterium vitis strain CG412

Toxin (Protein)


Gene name yoeB Uniprot ID A0A368NJ19
Locus tag AVCG412_RS10580 Protein ID WP_060719886.1
Coordinates 2221945..2222217 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A368NHU1
Locus tag AVCG412_RS10575 Protein ID WP_060719885.1
Coordinates 2221669..2221941 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AVCG412_RS10560 (AVCG412_10530) 2217534..2218115 + 582 WP_060719882.1 ATP-dependent Clp protease proteolytic subunit -
AVCG412_RS10565 (AVCG412_10535) 2218288..2219472 + 1185 WP_114386954.1 benzoate/H(+) symporter BenE family transporter -
AVCG412_RS10570 (AVCG412_10540) 2219820..2221526 + 1707 WP_060719884.1 2-isopropylmalate synthase -
AVCG412_RS10575 (AVCG412_10545) 2221669..2221941 + 273 WP_060719885.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AVCG412_RS10580 (AVCG412_10550) 2221945..2222217 + 273 WP_060719886.1 Txe/YoeB family addiction module toxin Toxin
AVCG412_RS10585 (AVCG412_10555) 2222234..2222665 - 432 WP_060719887.1 Lrp/AsnC family transcriptional regulator -
AVCG412_RS10590 (AVCG412_10560) 2222787..2223908 + 1122 WP_060719888.1 saccharopine dehydrogenase family protein -
AVCG412_RS10595 (AVCG412_10565) 2224033..2224461 + 429 WP_234613960.1 hypothetical protein -
AVCG412_RS10600 (AVCG412_10570) 2224667..2226823 + 2157 WP_060719957.1 type VI secretion system tip protein TssI/VgrG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10576.10 Da        Isoelectric Point: 9.5183

>T162203 WP_060719886.1 NZ_CP055265:2221945-2222217 [Agrobacterium vitis]
MKLGWTENAWDDYEFWLQTDLKMVSKINDLIRNAKRTPFTGLGKPEPLKGDLAGFWSRRIAGDHRLVYCVSGSGQEQRLD
IVQCRYHYRK

Download         Length: 273 bp

>T162203 NZ_CP071686:c4488995-4488684 [Salmonella sp. SAL-007]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10283.33 Da        Isoelectric Point: 4.5452

>AT162203 WP_060719885.1 NZ_CP055265:2221669-2221941 [Agrobacterium vitis]
MTNVRFTEFRQNFAHHFDSVLESRAPLLVTRQGKEAVVVIAEGEYESMQETLHLLSNPANAERLRDSIEQLRQGKVTDRD
PTEPDDGQDT

Download         Length: 273 bp

>AT162203 NZ_CP071686:c4488683-4488393 [Salmonella sp. SAL-007]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A368NJ19

Antitoxin

Source ID Structure
AlphaFold DB A0A368NHU1

References