160595

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 190222..191072 Replicon plasmid unnamed3
Accession NZ_CP054911
Organism Pantoea ananatis strain FDAARGOS_680

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag FOB88_RS02710 Protein ID WP_176017447.1
Coordinates 190587..191072 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag FOB88_RS02705 Protein ID WP_176017446.1
Coordinates 190222..190563 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB88_RS02695 186212..187621 - 1410 WP_176017444.1 NarK family nitrate/nitrite MFS transporter -
FOB88_RS02700 188078..189001 + 924 WP_176017445.1 IS5 family transposase -
FOB88_RS02705 190222..190563 + 342 WP_176017446.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
FOB88_RS02710 190587..191072 + 486 WP_176017447.1 type II toxin-antitoxin system YhaV family toxin Toxin
FOB88_RS02715 191738..191893 + 156 Protein_186 IS110 family transposase -
FOB88_RS02720 191957..192448 + 492 Protein_187 DMT family transporter -
FOB88_RS02725 192616..193577 - 962 Protein_188 ExeA family protein -
FOB88_RS02730 193510..193988 - 479 Protein_189 IS481 family transposase -
FOB88_RS02735 193990..194112 - 123 Protein_190 recombinase family protein -
FOB88_RS02740 194623..195015 + 393 WP_176017448.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fliC 1..218767 218767
- flank IS/Tn - - 188078..189001 923


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(11-147)

Antitoxin

PrlF antitoxin

(15-113)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 18803.42 Da        Isoelectric Point: 8.1330

>T160595 WP_176017447.1 NZ_CP054911:190587-191072 [Pantoea ananatis]
MENSELNGWKICFHDCFVKQISSLAQYVAELQKFKPDEYQRKKETKLLAAIEKVIKDKISVNPLDTQFRQGDTLGHNNKH
WFRAKFMQQFRLFFRCSEEHKTIIICWVNDFDTLRAYGSKNDAYKVFASMLKAGNPPDDWEELVSQTKSAGSIPGFLQNQ
E

Download         Length: 486 bp

>T160595 NZ_CP070586:840284-840694 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGATGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12697.34 Da        Isoelectric Point: 4.5112

>AT160595 WP_176017446.1 NZ_CP054911:190222-190563 [Pantoea ananatis]
MVNNFRMADVSLRAESRLTERSQTTIPAAIRDALHLKPGEYIHYTLLAGGKVIMSRNEDEQDDPVVSQFLNFLENDMMKN
PQNIHQVPTAFWAGIQKLTAGVEVDLDAPLTDD

Download         Length: 342 bp

>AT160595 NZ_CP070586:840037-840303 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References