Detailed information of TA system TA160495

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 6675..6823
• Replicon: plasmid pUTI-045-2
• Accession: NZ_CP054833
• Organism: Staphylococcus saprophyticus strain UTI-045

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: HSZ48_RS13430
• Protein ID: WP_011276848.1
• Coordinates: 6728..6823 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	6675..6710 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HSZ48_RS13400	2334..2633	-	300	Protein_2	hypothetical protein	-
HSZ48_RS13405	2693..3367	-	675	WP_001105987.1	IS6-like element IS257 family transposase	-
HSZ48_RS13410	3950..4558	-	609	WP_002380765.1	recombinase family protein	-
HSZ48_RS13415	4846..5511	+	666	WP_012816722.1	DUF5079 family protein	-
HSZ48_RS13420	5511..5820	+	310	Protein_6	DUF5085 family protein	-
HSZ48_RS13425	5870..6457	+	588	WP_012816724.1	DUF5080 family protein	-
-	6675..6710	-	36	NuclAT_0	-	Antitoxin
HSZ48_RS13430	6728..6823	-	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
HSZ48_RS13435	7246..7473	+	228	WP_145381811.1	hypothetical protein	-
HSZ48_RS13440	9177..10166	+	990	WP_041080315.1	biotin synthase BioB	-
HSZ48_RS13445	10398..10814	+	417	WP_069821423.1	VOC family protein	-
HSZ48_RS13450	11166..11666	-	501	WP_175268022.1	GNAT family N-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..19933	19933
	-	flank	IS/Tn	-	-	2693..3367	674

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T160495 WP_011276848.1 NZ_CP054833:c6823-6728 [Staphylococcus saprophyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T160495 NZ_CP070534:c1071953-1071651 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
CTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCTGTGGGAGAAGGTATCAGTGAACTGAGGATTC
ACTTTGGCCCGGGCTACAGGATCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin

Nucleotide

• Length: 36 bp

>AT160495 NZ_CP054833:c6710-6675 [Staphylococcus saprophyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin