Detailed information of TA system TA160492

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 13689..13837
• Replicon: plasmid pUTI-045-1
• Accession: NZ_CP054832
• Organism: Staphylococcus saprophyticus strain UTI-045

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: HSZ48_RS13060
• Protein ID: WP_107549835.1
• Coordinates: 13689..13784 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	13802..13837 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HSZ48_RS13025	8939..9226	+	288	WP_069805294.1	hypothetical protein	-
HSZ48_RS13030	9468..9626	+	159	WP_164971880.1	hypothetical protein	-
HSZ48_RS13035	10148..10553	-	406	Protein_8	sulfite exporter TauE/SafE family protein	-
HSZ48_RS13040	10545..11215	+	671	Protein_9	NAD(P)/FAD-dependent oxidoreductase	-
HSZ48_RS13045	11524..11619	+	96	WP_115353180.1	type I toxin-antitoxin system Fst family toxin	-
HSZ48_RS13050	11782..12882	-	1101	WP_129369067.1	glycerol dehydrogenase	-
HSZ48_RS13055	13227..13499	+	273	WP_069804829.1	hypothetical protein	-
HSZ48_RS13060	13689..13784	+	96	WP_107549835.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	13802..13837	+	36	NuclAT_0	-	Antitoxin
HSZ48_RS13065	13942..14799	+	858	WP_069804831.1	DNA-processing protein DprA	-
HSZ48_RS13070	14796..15956	+	1161	WP_069804833.1	phosphoribosyltransferase	-
HSZ48_RS13075	16004..16549	-	546	WP_069804836.1	recombinase family protein	-
HSZ48_RS13080	16789..17055	-	267	WP_129369059.1	GNAT family N-acetyltransferase	-
HSZ48_RS13085	17010..17273	-	264	WP_145464977.1	GNAT family N-acetyltransferase	-
HSZ48_RS13090	17498..17935	+	438	WP_129369061.1	hypothetical protein	-
HSZ48_RS13095	18099..18266	-	168	WP_164971879.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..74014	74014

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3637.41 Da
• Isoelectric Point: 9.5124

>T160492 WP_107549835.1 NZ_CP054832:13689-13784 [Staphylococcus saprophyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKEK

Nucleotide

• Length: 96 bp

>T160492 NZ_CP070530:c13945-12620 [Enterobacter hormaechei]
ATGAGCCGGAAACAGCAGCGTCTGGCAATCTGGATGAACGGAATCAAAGTCGGATACTGGGAAAAAAGTAAAGGGGTAGA
CAGCTTACAATACCTTCCTGACTGGAGTGCAGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTCCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTTCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACAGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGCGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGAACAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAAACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCATTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAAGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAGTTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCACTCTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin

Nucleotide

• Length: 36 bp

>AT160492 NZ_CP054832:13802-13837 [Staphylococcus saprophyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin