Detailed information of TA system TA160489

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2629714..2629871
• Replicon: chromosome
• Accession: NZ_CP054831
• Organism: Staphylococcus saprophyticus strain UTI-045

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HSZ48_RS12945
• Protein ID: WP_002441941.1
• Coordinates: 2629776..2629871 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2629714..2629747 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HSZ48_RS12920	2625502..2626335	+	834	WP_069795006.1	aldo/keto reductase	-
HSZ48_RS12925	2626802..2627101	-	300	WP_011304021.1	hypothetical protein	-
HSZ48_RS12930	2627478..2627711	+	234	WP_011304022.1	ferrous iron transport protein A	-
HSZ48_RS12935	2627772..2627837	-	66	WP_162009580.1	type I toxin-antitoxin system Fst family toxin	-
HSZ48_RS12940	2628025..2629425	-	1401	WP_069819373.1	RES family NAD+ phosphorylase	-
-	2629714..2629747	+	34	-	-	Antitoxin
HSZ48_RS12945	2629776..2629871	-	96	WP_002441941.1	type I toxin-antitoxin system Fst family toxin	Toxin
HSZ48_RS12950	2630174..2630932	-	759	WP_011304024.1	MerR family transcriptional regulator	-
HSZ48_RS12955	2631042..2631605	-	564	WP_011304025.1	helix-turn-helix domain-containing protein	-
HSZ48_RS12960	2631799..2633256	-	1458	WP_011304026.1	carbon starvation protein A	-
HSZ48_RS12965	2633464..2634303	-	840	WP_002481957.1	ParB/RepB/Spo0J family partition protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3560.34 Da
• Isoelectric Point: 9.9256

>T160489 WP_002441941.1 NZ_CP054831:c2629871-2629776 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Nucleotide

• Length: 96 bp

>T160489 NZ_CP070528:c4668127-4667594 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGTATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 34 bp

>AT160489 NZ_CP054831:2629714-2629747 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin