Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 1264649..1264871 | Replicon | chromosome |
Accession | NZ_CP054665 | ||
Organism | Escherichia coli strain IGC_EcoliInv_1.1 |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | D3H2K1 |
Locus tag | HUR94_RS06245 | Protein ID | WP_000170955.1 |
Coordinates | 1264649..1264756 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 1264804..1264871 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HUR94_RS06215 (1260505) | 1260505..1261338 | + | 834 | WP_000456467.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
HUR94_RS06220 (1261335) | 1261335..1261727 | + | 393 | WP_000200374.1 | invasion regulator SirB2 | - |
HUR94_RS06225 (1261731) | 1261731..1262540 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
HUR94_RS06230 (1262576) | 1262576..1263430 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
HUR94_RS06235 (1263579) | 1263579..1263686 | - | 108 | WP_000170955.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_34 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_34 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_34 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_34 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_36 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_36 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_36 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_36 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_38 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_38 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_38 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_38 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_40 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_40 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_40 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_40 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_42 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_42 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_42 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_42 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_44 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_44 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_44 | - | - |
- (1263734) | 1263734..1263800 | + | 67 | NuclAT_44 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_18 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_18 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_18 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_18 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_21 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_21 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_21 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_21 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_24 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_24 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_24 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_24 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_27 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_27 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_27 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_27 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_30 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_30 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_30 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_30 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_33 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_33 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_33 | - | - |
- (1263736) | 1263736..1263801 | + | 66 | NuclAT_33 | - | - |
HUR94_RS06240 (1264114) | 1264114..1264221 | - | 108 | WP_000170963.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_35 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_35 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_35 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_35 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_37 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_37 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_37 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_37 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_39 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_39 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_39 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_39 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_41 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_41 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_41 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_41 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_43 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_43 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_43 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_43 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_45 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_45 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_45 | - | - |
- (1264270) | 1264270..1264335 | + | 66 | NuclAT_45 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_17 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_17 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_17 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_17 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_20 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_20 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_20 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_20 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_23 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_23 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_23 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_23 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_26 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_26 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_26 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_26 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_29 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_29 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_29 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_29 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_32 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_32 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_32 | - | - |
- (1264269) | 1264269..1264336 | + | 68 | NuclAT_32 | - | - |
HUR94_RS06245 (1264649) | 1264649..1264756 | - | 108 | WP_000170955.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_16 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_16 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_16 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_16 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_19 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_19 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_19 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_19 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_22 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_22 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_22 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_22 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_25 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_25 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_25 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_25 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_28 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_28 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_28 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_28 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_31 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_31 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_31 | - | Antitoxin |
- (1264804) | 1264804..1264871 | + | 68 | NuclAT_31 | - | Antitoxin |
HUR94_RS06250 (1265160) | 1265160..1266260 | - | 1101 | WP_000063607.1 | sodium-potassium/proton antiporter ChaA | - |
HUR94_RS06255 (1266530) | 1266530..1266760 | + | 231 | WP_001146444.1 | putative cation transport regulator ChaB | - |
HUR94_RS06260 (1266918) | 1266918..1267613 | + | 696 | WP_001336325.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
HUR94_RS06265 (1267657) | 1267657..1268010 | - | 354 | WP_001169669.1 | DsrE/F sulfur relay family protein YchN | - |
HUR94_RS06270 (1268195) | 1268195..1269589 | + | 1395 | WP_000086217.1 | inverse autotransporter invasin YchO | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4013.82 Da Isoelectric Point: 11.4779
>T160037 WP_000170955.1 NZ_CP054665:c1264756-1264649 [Escherichia coli]
MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK
MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK
Download Length: 108 bp
>T160037 NZ_CP070283:146012-146317 [Escherichia albertii]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCTTGGCCAGTGCCCGCCTGCTGTCAGATAAAGTCTCCCGTGAGCTTTACCCGGTGG
TGCTTGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGTCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGGGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCTTGGCCAGTGCCCGCCTGCTGTCAGATAAAGTCTCCCGTGAGCTTTACCCGGTGG
TGCTTGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGTCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGGGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA
Antitoxin
Download Length: 68 bp
>AT160037 NZ_CP054665:1264804-1264871 [Escherichia coli]
GTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCTCT
GTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|