Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 579113..579807 Replicon chromosome
Accession NZ_CP054619
Organism Azospirillum oryzae strain KACC 14407

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HUE56_RS11735 Protein ID WP_149197840.1
Coordinates 579448..579807 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HUE56_RS11730 Protein ID WP_149197839.1
Coordinates 579113..579451 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUE56_RS11725 576268..578961 + 2694 WP_149197838.1 pyruvate, phosphate dikinase -
HUE56_RS11730 579113..579451 - 339 WP_149197839.1 XRE family transcriptional regulator Antitoxin
HUE56_RS11735 579448..579807 - 360 WP_149197840.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HUE56_RS11740 579880..580026 + 147 WP_211101041.1 hypothetical protein -
HUE56_RS11745 580401..580670 - 270 WP_149197841.1 type II toxin-antitoxin system RelE/ParE family toxin -
HUE56_RS11750 580661..580834 - 174 WP_149197842.1 antitoxin -
HUE56_RS11755 581128..582288 - 1161 WP_174757212.1 XRE family transcriptional regulator -
HUE56_RS11760 582367..583065 - 699 WP_149197844.1 hypothetical protein -
HUE56_RS11765 583338..583703 - 366 WP_149197845.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 12982.84 Da        Isoelectric Point: 10.6473

>T159979 WP_149197840.1 NZ_CP054619:c579807-579448 [Azospirillum oryzae]
MHTVLFHTAFAAEFRALPHAVRIDLAAAAKVLGERGPALGRPHVDTLNGSRHANMKELRFKSNGGVWRVAFAFDPKRNAV
VLVAGDKSGVSEKRFYASLIATADSRYDDHLSDLKGTKP

Download         Length: 360 bp

>T159979 NZ_CP070229:3196754-3196861 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12155.83 Da        Isoelectric Point: 4.7147

>AT159979 WP_149197839.1 NZ_CP054619:c579451-579113 [Azospirillum oryzae]
MTATIPFDQILSEMTDDERAAVDARAAGMLAEIDGLAELRRLAELTQGQVAETLNVKQPTVHQIEKRTDLYLSTLRRFVE
AAGGELELRVSLPGKGAFKLTGIGELTSGSQR

Download         Length: 339 bp

>AT159979 NZ_CP070229:c3196706-3196640 [Escherichia coli]
GGTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References