Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 286207..286720 Replicon plasmid unnamed2
Accession NZ_CP054616
Organism Azospirillum oryzae strain KACC 14407

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HUE56_RS02405 Protein ID WP_149199333.1
Coordinates 286454..286720 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A6N1ADX4
Locus tag HUE56_RS02400 Protein ID WP_044552781.1
Coordinates 286207..286473 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUE56_RS02375 281475..282644 - 1170 WP_149199328.1 thiolase family protein -
HUE56_RS02380 282641..284128 - 1488 WP_149199329.1 AMP-binding protein -
HUE56_RS02385 284133..284678 - 546 WP_174757030.1 biotin transporter BioY -
HUE56_RS02390 284709..285359 - 651 WP_149199331.1 energy-coupling factor transporter transmembrane protein EcfT -
HUE56_RS02395 285359..286033 - 675 WP_149199332.1 ATP-binding cassette domain-containing protein -
HUE56_RS02400 286207..286473 + 267 WP_044552781.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HUE56_RS02405 286454..286720 + 267 WP_149199333.1 Txe/YoeB family addiction module toxin Toxin
HUE56_RS02410 286774..287538 - 765 WP_174757032.1 amino acid ABC transporter ATP-binding protein -
HUE56_RS02415 287601..288305 - 705 WP_149199334.1 amino acid ABC transporter permease -
HUE56_RS02420 288310..288957 - 648 WP_149199335.1 amino acid ABC transporter permease -
HUE56_RS02425 289029..289847 - 819 WP_149199390.1 transporter substrate-binding domain-containing protein -
HUE56_RS02430 289926..290837 - 912 WP_149199336.1 GntR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..668146 668146


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10338.76 Da        Isoelectric Point: 9.4084

>T159978 WP_149199333.1 NZ_CP054616:286454-286720 [Azospirillum oryzae]
MKKVWTDGAWEDYLYWQKNERAVLKKVNDLIRDTERNPFSGLGKPEPLKEGLAGWWSRRITGEHRLVYRVTGSGDAQALE
ILACRYHY

Download         Length: 267 bp

>T159978 NZ_CP070229:3196271-3196378 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGTTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9798.17 Da        Isoelectric Point: 4.6768

>AT159978 WP_044552781.1 NZ_CP054616:286207-286473 [Azospirillum oryzae]
MGHISYTDLRNNLASVMDEVCDSRAPLTVTRQKGRSVVMISEEEFEGLMETLHLLKSPKNAERLLKGIAQLDAGKGIERD
ILNEEGLD

Download         Length: 267 bp

>AT159978 NZ_CP070229:c3196223-3196157 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6N1ADX4

References