Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 562550..563064 Replicon chromosome
Accession NZ_CP054599
Organism Sulfitobacter pseudonitzschiae strain H46

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HT745_RS02785 Protein ID WP_127044728.1
Coordinates 562798..563064 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HT745_RS02780 Protein ID WP_174861630.1
Coordinates 562550..562801 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HT745_RS02760 558267..559547 - 1281 WP_174861626.1 TRAP transporter large permease -
HT745_RS02765 559547..560092 - 546 WP_174861627.1 TRAP transporter small permease -
HT745_RS02770 560154..561152 - 999 WP_174861628.1 TRAP transporter substrate-binding protein DctP -
HT745_RS02775 561296..562222 - 927 WP_174861629.1 LysR family transcriptional regulator -
HT745_RS02780 562550..562801 + 252 WP_174861630.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HT745_RS02785 562798..563064 + 267 WP_127044728.1 Txe/YoeB family addiction module toxin Toxin
HT745_RS02790 563216..563944 + 729 WP_174861631.1 ParA family protein -
HT745_RS02795 563941..564255 + 315 WP_174861632.1 hypothetical protein -
HT745_RS02800 564252..565316 - 1065 WP_074637844.1 replication initiator protein A -
HT745_RS02805 565570..566277 - 708 WP_037931728.1 IS6 family transposase -
HT745_RS02810 566424..567236 - 813 WP_037931725.1 IclR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10379.73 Da        Isoelectric Point: 9.8183

>T159970 WP_127044728.1 NZ_CP054599:562798-563064 [Sulfitobacter pseudonitzschiae]
VKLVFSNQAWEDYQYWVSTNDKVRDRINELIKQCKRTPFKGTGKPEPLKGDLTGWWSRRISQEDRMVYRVSGAGDGQSLE
IAQLRFHY

Download         Length: 267 bp

>T159970 NZ_CP070229:920215-920709 [Escherichia coli]
ATGATTCAGGCCCCCGAGCCACTCATGGCAAGGCATCAATTCACCTCTTTTTGCTCGGGAGTAGAAACGATGGATAACTG
GCTAAAGCAGAGAGCCCTAAAAAATCAGCTTGCCGGCGCATCACGTACATTTGTTAGCTGTGATACGTATAGCAACGTTT
TGGCATATTATTCGCTTGCTTCCAGCGCCGTTGAAACGTATGTCGCGACAGGACGATTTCGCCGAAATATGCCAGAACCG
ATCCCTGTTGTAGTACTTGGTCGTCTGGCAATAGATAAATCATTACAGGGTCAGGGCATCGGTCGTGCGATGGTCAGAGA
TGCCGGTCTACGAGTACTACAGGCGGCTGAAGTCATTGGTATTCGCGGAATGTTGGTCCATGCGTTATCAGACCAGGCCC
GTGAGTTTTATCTGCGAGTGGGGTTTGAACCATCGCCTGTCGATTCTATGATACTGATGGCAACATTGGCTGATTTGCAG
GAATGTCTTAAATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9195.41 Da        Isoelectric Point: 5.6939

>AT159970 WP_174861630.1 NZ_CP054599:562550-562801 [Sulfitobacter pseudonitzschiae]
MDVMTYSDARAQLKGVMDRAIHDKQEVVVTRKKGESVVVVSLETWNAVNETLHLLSTPKNASRLRASIAQLDAGTGEERE
LTE

Download         Length: 252 bp

>AT159970 NZ_CP070229:919925-920218 [Escherichia coli]
ATGCCAGCAGCCAATAACATTCCAACCAGGCGCGAATCTTTAAATTTGCGCATAAAACCCGCAGAACGCGATCTTATTGA
CCGGGCCGCTAAAGCCCGAGGAAAAAATCGCACCGAATTTGTCCTTGAGGCCGCCAGAGCCGCAGCTGAAGAGGCGCTCA
TTGAGCAGAGAATTTTCAGGATCGATTCTGATGATTACCAGCTATTTTTGAATCGTCTGGATCATCCCCCCGCGCCCAAT
GCTGCATTACGCAAAACCATGCAAACACCCGCGCCGTGGGAGCAAAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References