Detailed information of TA system TA159953

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrE/-
• Location: 2280100..2280317
• Replicon: chromosome
• Accession: NZ_CP054584
• Organism: Bacillus halotolerans strain KKD1

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: HT135_RS11525
• Protein ID: WP_017696861.1
• Coordinates: 2280100..2280276 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2280217..2280317 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HT135_RS11505	2276104..2277972	-	1869	WP_106019955.1	OmpH family outer membrane protein	-
HT135_RS11510	2278299..2279516	-	1218	WP_106019956.1	hypothetical protein	-
HT135_RS11515	2279598..2279786	-	189	WP_106019957.1	hypothetical protein	-
HT135_RS11520	2279831..2280046	-	216	WP_106019958.1	hypothetical protein	-
HT135_RS11525	2280100..2280276	-	177	WP_017696861.1	hypothetical protein	Toxin
-	2280217..2280317	+	101	NuclAT_0	-	Antitoxin
-	2280217..2280317	+	101	NuclAT_0	-	Antitoxin
-	2280217..2280317	+	101	NuclAT_0	-	Antitoxin
-	2280217..2280317	+	101	NuclAT_0	-	Antitoxin
HT135_RS11530	2280510..2280731	-	222	WP_106019959.1	hypothetical protein	-
HT135_RS11535	2280812..2281417	-	606	WP_106019960.1	hypothetical protein	-
HT135_RS11540	2281637..2281963	-	327	WP_106019961.1	helix-turn-helix domain-containing protein	-
HT135_RS11545	2282915..2283109	+	195	WP_072692657.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2206005..2339011	133006

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6878.45 Da
• Isoelectric Point: 12.8833

>T159953 WP_017696861.1 NZ_CP054584:c2280276-2280100 [Bacillus halotolerans]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T159953 NZ_CP070227:c2230784-2230677 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCGTGATTTTCTGGCACGACCTGGCAGCACCGATCCTTGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT159953 NZ_CP054584:2280217-2280317 [Bacillus halotolerans]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin