Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2590976..2591133 Replicon chromosome
Accession NZ_CP054575
Organism Staphylococcus saprophyticus strain UTI-050

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag HSZ50_RS12870 Protein ID WP_002441941.1
Coordinates 2591038..2591133 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2590976..2591009 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HSZ50_RS12840 2586764..2587597 + 834 WP_069795006.1 aldo/keto reductase -
HSZ50_RS12845 2588064..2588363 - 300 WP_011304021.1 hypothetical protein -
HSZ50_RS12850 2588740..2588973 + 234 WP_011304022.1 ferrous iron transport protein A -
HSZ50_RS12855 2589034..2589099 - 66 WP_162009580.1 type I toxin-antitoxin system Fst family toxin -
HSZ50_RS12860 2589287..2589874 - 588 WP_174605046.1 RES family NAD+ phosphorylase -
HSZ50_RS12865 2589862..2590680 - 819 WP_174605047.1 hypothetical protein -
- 2590976..2591009 + 34 - - Antitoxin
HSZ50_RS12870 2591038..2591133 - 96 WP_002441941.1 type I toxin-antitoxin system Fst family toxin Toxin
HSZ50_RS12875 2591436..2592194 - 759 Protein_2489 MerR family transcriptional regulator -
HSZ50_RS12880 2592304..2592867 - 564 WP_047505113.1 helix-turn-helix domain-containing protein -
HSZ50_RS12885 2593061..2594518 - 1458 WP_011304026.1 carbon starvation protein A -
HSZ50_RS12890 2594726..2595565 - 840 WP_002481957.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3560.34 Da        Isoelectric Point: 9.9256

>T159917 WP_002441941.1 NZ_CP054575:c2591133-2591038 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Download         Length: 96 bp

>T159917 NZ_CP070170:3541042-3541260 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 34 bp

>AT159917 NZ_CP054575:2590976-2591009 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References