Detailed information of TA system TA159755

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 545730..545887
• Replicon: chromosome
• Accession: NZ_CP054444
• Organism: Staphylococcus saprophyticus strain UTI-056

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HSZ51_RS02740
• Protein ID: WP_002441941.1
• Coordinates: 545792..545887 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	545730..545763 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HSZ51_RS02715	541517..542350	+	834	WP_048787569.1	aldo/keto reductase	-
HSZ51_RS02720	542817..543116	-	300	WP_011304021.1	hypothetical protein	-
HSZ51_RS02725	543493..543726	+	234	WP_048787568.1	ferrous iron transport protein A	-
HSZ51_RS02730	543787..543852	-	66	WP_162009580.1	type I toxin-antitoxin system Fst family toxin	-
HSZ51_RS02735	544040..545434	-	1395	WP_048787567.1	RES family NAD+ phosphorylase	-
-	545730..545763	+	34	-	-	Antitoxin
HSZ51_RS02740	545792..545887	-	96	WP_002441941.1	type I toxin-antitoxin system Fst family toxin	Toxin
HSZ51_RS02745	546190..546948	-	759	WP_011304024.1	MerR family transcriptional regulator	-
HSZ51_RS02750	547058..547621	-	564	WP_048787566.1	helix-turn-helix domain-containing protein	-
HSZ51_RS02755	547815..549272	-	1458	WP_011304026.1	carbon starvation protein A	-
HSZ51_RS02760	549480..550319	-	840	WP_002481957.1	ParB/RepB/Spo0J family partition protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3560.34 Da
• Isoelectric Point: 9.9256

>T159755 WP_002441941.1 NZ_CP054444:c545887-545792 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Nucleotide

• Length: 96 bp

>T159755 NZ_CP070124:4925796-4925948 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin

Nucleotide

• Length: 34 bp

>AT159755 NZ_CP054444:545730-545763 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin