Detailed information of TA system TA159752

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2540177..2540334
• Replicon: chromosome
• Accession: NZ_CP054440
• Organism: Staphylococcus saprophyticus strain UTI-058y

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HSZ52_RS12545
• Protein ID: WP_002441941.1
• Coordinates: 2540239..2540334 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2540177..2540210 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HSZ52_RS12520	2535964..2536797	+	834	WP_048787569.1	aldo/keto reductase	-
HSZ52_RS12525	2537264..2537563	-	300	WP_011304021.1	hypothetical protein	-
HSZ52_RS12530	2537940..2538173	+	234	WP_048787568.1	ferrous iron transport protein A	-
HSZ52_RS12535	2538234..2538299	-	66	WP_162009580.1	type I toxin-antitoxin system Fst family toxin	-
HSZ52_RS12540	2538487..2539881	-	1395	WP_048787567.1	RES family NAD+ phosphorylase	-
-	2540177..2540210	+	34	-	-	Antitoxin
HSZ52_RS12545	2540239..2540334	-	96	WP_002441941.1	type I toxin-antitoxin system Fst family toxin	Toxin
HSZ52_RS12550	2540637..2541395	-	759	WP_011304024.1	MerR family transcriptional regulator	-
HSZ52_RS12555	2541505..2542068	-	564	WP_048787566.1	helix-turn-helix domain-containing protein	-
HSZ52_RS12560	2542262..2543719	-	1458	WP_011304026.1	carbon starvation protein A	-
HSZ52_RS12565	2543927..2544766	-	840	WP_002481957.1	ParB/RepB/Spo0J family partition protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3560.34 Da
• Isoelectric Point: 9.9256

>T159752 WP_002441941.1 NZ_CP054440:c2540334-2540239 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Nucleotide

• Length: 96 bp

>T159752 NZ_CP070124:c4428460-4428158 [Escherichia coli]
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATTGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA

Antitoxin

Nucleotide

• Length: 34 bp

>AT159752 NZ_CP054440:2540177-2540210 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin