Detailed information of TA system TA159740

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2559190..2559347
• Replicon: chromosome
• Accession: NZ_CP054434
• Organism: Staphylococcus saprophyticus strain UTI-035

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HSZ47_RS12555
• Protein ID: WP_002441941.1
• Coordinates: 2559252..2559347 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2559190..2559223 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HSZ47_RS12530	2554977..2555810	+	834	WP_048787569.1	aldo/keto reductase	-
HSZ47_RS12535	2556277..2556576	-	300	WP_011304021.1	hypothetical protein	-
HSZ47_RS12540	2556953..2557186	+	234	WP_011304022.1	ferrous iron transport protein A	-
HSZ47_RS12545	2557247..2557312	-	66	WP_162009580.1	type I toxin-antitoxin system Fst family toxin	-
HSZ47_RS12550	2557500..2558894	-	1395	WP_069822293.1	RES family NAD+ phosphorylase	-
-	2559190..2559223	+	34	-	-	Antitoxin
HSZ47_RS12555	2559252..2559347	-	96	WP_002441941.1	type I toxin-antitoxin system Fst family toxin	Toxin
HSZ47_RS12560	2559650..2560408	-	759	WP_174538817.1	MerR family transcriptional regulator	-
HSZ47_RS12565	2560519..2561082	-	564	WP_063488859.1	helix-turn-helix domain-containing protein	-
HSZ47_RS12570	2561276..2562733	-	1458	WP_063488860.1	carbon starvation protein A	-
HSZ47_RS12575	2562941..2563780	-	840	WP_002481957.1	ParB/RepB/Spo0J family partition protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3560.34 Da
• Isoelectric Point: 9.9256

>T159740 WP_002441941.1 NZ_CP054434:c2559347-2559252 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Nucleotide

• Length: 96 bp

>T159740 NZ_CP070124:1107730-1107837 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCACGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 34 bp

>AT159740 NZ_CP054434:2559190-2559223 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin