Detailed information of TA system TA159541

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 2098149..2098520
• Replicon: chromosome
• Accession: NZ_CP054371
• Organism: Escherichia coli strain SCU-316

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: -
• Locus tag: HPE41_RS09750
• Protein ID: WP_053889809.1
• Coordinates: 2098326..2098520 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	2098149..2098327 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HPE41_RS09725	2094104..2095477	+	1374	WP_000123746.1	ATP-dependent RNA helicase DbpA	-
HPE41_RS09730	2095606..2096541	-	936	WP_001157403.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
HPE41_RS09735	2096593..2097828	-	1236	WP_112033623.1	site-specific integrase	-
HPE41_RS09740	2097830..2098045	-	216	WP_000079604.1	excisionase XisR	-
HPE41_RS09745	2098124..2098333	-	210	WP_000276809.1	double-strand break reduction protein RcbA	-
-	2098149..2098327	+	179	NuclAT_0	-	Antitoxin
-	2098149..2098327	+	179	NuclAT_0	-	Antitoxin
-	2098149..2098327	+	179	NuclAT_0	-	Antitoxin
-	2098149..2098327	+	179	NuclAT_0	-	Antitoxin
HPE41_RS09750	2098326..2098520	-	195	WP_053889809.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
HPE41_RS09755	2098577..2099386	-	810	WP_000166319.1	recombination protein RecT	-
HPE41_RS09760	2099379..2101979	-	2601	WP_000105139.1	exodeoxyribonuclease VIII	-
HPE41_RS09765	2102081..2102356	-	276	WP_000632297.1	protein RacC	-
HPE41_RS09770	2102431..2102601	-	171	WP_001352098.1	conserved protein, Rac prophage	-
HPE41_RS09775	2102601..2102822	-	222	WP_000560223.1	killing protein KilR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2096593..2144199	47606

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7032.91 Da
• Isoelectric Point: 8.9538

>T159541 WP_053889809.1 NZ_CP054371:c2098520-2098326 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGIHV

Nucleotide

• Length: 195 bp

>T159541 NZ_CP070071:4083496-4083603 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT159541 NZ_CP054371:2098149-2098327 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Structures

Antitoxin