Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 606191..606693 Replicon chromosome
Accession NZ_CP054301
Organism Marinomonas primoryensis strain MPKMM3633

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MP3633_RS02780 Protein ID WP_176334391.1
Coordinates 606430..606693 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MP3633_RS02775 Protein ID WP_176334390.1
Coordinates 606191..606433 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MP3633_RS02745 601335..601790 - 456 WP_176334384.1 GNAT family N-acetyltransferase -
MP3633_RS02750 601906..602367 + 462 WP_176334385.1 GNAT family N-acetyltransferase -
MP3633_RS02755 602364..602627 - 264 WP_176334386.1 DUF3820 family protein -
MP3633_RS02760 602692..603582 - 891 WP_176334387.1 LysR family transcriptional regulator -
MP3633_RS02765 603770..604888 + 1119 WP_176334388.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
MP3633_RS02770 604966..605796 + 831 WP_176334389.1 S-formylglutathione hydrolase -
MP3633_RS02775 606191..606433 + 243 WP_176334390.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MP3633_RS02780 606430..606693 + 264 WP_176334391.1 Txe/YoeB family addiction module toxin Toxin
MP3633_RS02785 606950..607768 + 819 WP_176334392.1 hypothetical protein -
MP3633_RS02790 608289..608720 + 432 WP_176334393.1 hypothetical protein -
MP3633_RS02795 608779..609933 + 1155 WP_176334394.1 amidohydrolase -
MP3633_RS02800 610041..610652 + 612 WP_176334395.1 LysE family translocator -
MP3633_RS02805 610725..611558 + 834 WP_176334396.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10129.71 Da        Isoelectric Point: 10.2671

>T159372 WP_176334391.1 NZ_CP054301:606430-606693 [Marinomonas primoryensis]
VTWTLVYTKQAQNDAKKLASSGLRSKAQELLNFIAQDPFQKPPPFEKLIGDLSGAYSRRINIQHRLVYQVLDAERMIKVL
RLWSHYE

Download         Length: 264 bp

>T159372 NZ_CP070026:c3732857-3732754 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8866.92 Da        Isoelectric Point: 4.1191

>AT159372 WP_176334390.1 NZ_CP054301:606191-606433 [Marinomonas primoryensis]
MAGITATEARGNLYRLIDETAASHEPITISGKRNNAVLVSEEDWSAIQETLFLLSVPKMRESIREGMDTPVSECDEGLDW

Download         Length: 243 bp

>AT159372 NZ_CP070026:3732716-3732987 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References