Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1554026..1554528 Replicon chromosome
Accession NZ_CP054258
Organism Treponema socranskii subsp. buccale strain ATCC 35534

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HRI97_RS07035 Protein ID WP_253724777.1
Coordinates 1554268..1554528 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HRI97_RS07030 Protein ID WP_253724775.1
Coordinates 1554026..1554268 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRI97_RS07010 (HRI97_07025) 1549390..1549743 + 354 WP_253724767.1 hypothetical protein -
HRI97_RS07015 (HRI97_07030) 1549985..1550407 + 423 WP_253724770.1 Fur family transcriptional regulator -
HRI97_RS07020 (HRI97_07035) 1550468..1553245 + 2778 WP_253724772.1 ankyrin repeat domain-containing protein -
HRI97_RS07025 (HRI97_07040) 1553255..1553644 + 390 WP_253724774.1 hypothetical protein -
HRI97_RS07030 (HRI97_07045) 1554026..1554268 + 243 WP_253724775.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HRI97_RS07035 (HRI97_07050) 1554268..1554528 + 261 WP_253724777.1 Txe/YoeB family addiction module toxin Toxin
HRI97_RS07040 (HRI97_07055) 1554896..1555168 - 273 WP_253724778.1 hypothetical protein -
HRI97_RS07045 (HRI97_07060) 1555300..1555626 + 327 WP_253724780.1 Trp family transcriptional regulator -
HRI97_RS07050 (HRI97_07065) 1555733..1556698 - 966 WP_253724781.1 ABC transporter ATP-binding protein -
HRI97_RS07055 (HRI97_07070) 1556695..1558890 - 2196 WP_253724782.1 dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10372.09 Da        Isoelectric Point: 10.4620

>T159226 WP_253724777.1 NZ_CP054258:1554268-1554528 [Treponema socranskii subsp. buccale]
MWTVVYSKQAAKDSKKIKQANLKQTVKHLIEIIKNNPFENPPPYEKLVGDLTGKYSRRINIRHRLVYEVFEKENTVRILR
MWTHYE

Download         Length: 261 bp

>T159226 NZ_CP069980:4427934-4428110 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTGGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCAAGGGCGACGCAGTGTCATGCCGCGTCACCCCAGTGATGAGATAAAAGAACCATTGCGTAAAGCAATCCTGAAGC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9048.24 Da        Isoelectric Point: 4.1813

>AT159226 WP_253724775.1 NZ_CP054258:1554026-1554268 [Treponema socranskii subsp. buccale]
MAVITATAARTNLYNLIDRTKDCHEPIIISGKRNNAVLISEDDWNAIQETLYLCSIPGMRESIIEASNEPLEESIKELDW

Download         Length: 243 bp

>AT159226 NZ_CP069980:4428156-4428572 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACAGTTGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ATGAGCTAATCCCGTTGCCTTCGCCATTAACTAACAACGATCACTTTATTGAAGTGCCTTTAAGTATCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGACGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAATTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References