Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 2448124..2448346 Replicon chromosome
Accession NZ_CP054232
Organism Escherichia coli strain EcPF7

Toxin (Protein)


Gene name ldrD Uniprot ID A0A0D6GD35
Locus tag HR071_RS11825 Protein ID WP_000170745.1
Coordinates 2448124..2448231 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 2448288..2448346 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HR071_RS11800 2443659..2443847 - 189 WP_001063314.1 YhjR family protein -
HR071_RS11805 2444120..2445691 + 1572 WP_001204941.1 cellulose biosynthesis protein BcsE -
HR071_RS11810 2445688..2445879 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
HR071_RS11815 2445876..2447555 + 1680 WP_000191553.1 cellulose biosynthesis protein BcsG -
HR071_RS11820 2447641..2447748 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
HR071_RS11825 2448124..2448231 - 108 WP_000170745.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 2448288..2448346 + 59 - - Antitoxin
HR071_RS11830 2448607..2448714 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
HR071_RS11835 2449190..2450461 + 1272 WP_001296513.1 amino acid permease -
HR071_RS11840 2450491..2451495 - 1005 WP_000103571.1 dipeptide ABC transporter ATP-binding subunit DppF -
HR071_RS11845 2451492..2452475 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3855.68 Da        Isoelectric Point: 9.0157

>T159135 WP_000170745.1 NZ_CP054232:c2448231-2448124 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVSWLNKRK

Download         Length: 108 bp

>T159135 NZ_CP069964:c45734-45447 [Klebsiella pneumoniae]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 59 bp

>AT159135 NZ_CP054232:2448288-2448346 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6GD35

Antitoxin

Download structure file

References