Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1664056..1664277 Replicon chromosome
Accession NZ_CP054169
Organism Escherichia coli strain STO_Bone1B

Toxin (Protein)


Gene name ldrD Uniprot ID E0IV43
Locus tag HRS04_RS08940 Protein ID WP_000170926.1
Coordinates 1664056..1664163 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1664216..1664277 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRS04_RS08910 (1659365) 1659365..1660447 + 1083 WP_000804726.1 peptide chain release factor 1 -
HRS04_RS08915 (1660447) 1660447..1661280 + 834 WP_000456571.1 peptide chain release factor N(5)-glutamine methyltransferase -
HRS04_RS08920 (1661277) 1661277..1661669 + 393 WP_000200392.1 invasion regulator SirB2 -
HRS04_RS08925 (1661673) 1661673..1662482 + 810 WP_001257044.1 invasion regulator SirB1 -
HRS04_RS08930 (1662518) 1662518..1663372 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
HRS04_RS08935 (1663521) 1663521..1663628 - 108 WP_000170954.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1663678) 1663678..1663741 + 64 NuclAT_16 - -
- (1663678) 1663678..1663741 + 64 NuclAT_16 - -
- (1663678) 1663678..1663741 + 64 NuclAT_16 - -
- (1663678) 1663678..1663741 + 64 NuclAT_16 - -
- (1663678) 1663678..1663741 + 64 NuclAT_19 - -
- (1663678) 1663678..1663741 + 64 NuclAT_19 - -
- (1663678) 1663678..1663741 + 64 NuclAT_19 - -
- (1663678) 1663678..1663741 + 64 NuclAT_19 - -
- (1663678) 1663678..1663741 + 64 NuclAT_22 - -
- (1663678) 1663678..1663741 + 64 NuclAT_22 - -
- (1663678) 1663678..1663741 + 64 NuclAT_22 - -
- (1663678) 1663678..1663741 + 64 NuclAT_22 - -
- (1663678) 1663678..1663741 + 64 NuclAT_25 - -
- (1663678) 1663678..1663741 + 64 NuclAT_25 - -
- (1663678) 1663678..1663741 + 64 NuclAT_25 - -
- (1663678) 1663678..1663741 + 64 NuclAT_25 - -
- (1663678) 1663678..1663741 + 64 NuclAT_28 - -
- (1663678) 1663678..1663741 + 64 NuclAT_28 - -
- (1663678) 1663678..1663741 + 64 NuclAT_28 - -
- (1663678) 1663678..1663741 + 64 NuclAT_28 - -
- (1663678) 1663678..1663741 + 64 NuclAT_31 - -
- (1663678) 1663678..1663741 + 64 NuclAT_31 - -
- (1663678) 1663678..1663741 + 64 NuclAT_31 - -
- (1663678) 1663678..1663741 + 64 NuclAT_31 - -
- (1663676) 1663676..1663742 + 67 NuclAT_44 - -
- (1663676) 1663676..1663742 + 67 NuclAT_44 - -
- (1663676) 1663676..1663742 + 67 NuclAT_44 - -
- (1663676) 1663676..1663742 + 67 NuclAT_44 - -
- (1663676) 1663676..1663742 + 67 NuclAT_47 - -
- (1663676) 1663676..1663742 + 67 NuclAT_47 - -
- (1663676) 1663676..1663742 + 67 NuclAT_47 - -
- (1663676) 1663676..1663742 + 67 NuclAT_47 - -
- (1663676) 1663676..1663742 + 67 NuclAT_50 - -
- (1663676) 1663676..1663742 + 67 NuclAT_50 - -
- (1663676) 1663676..1663742 + 67 NuclAT_50 - -
- (1663676) 1663676..1663742 + 67 NuclAT_50 - -
HRS04_RS08940 (1664056) 1664056..1664163 - 108 WP_000170926.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (1664216) 1664216..1664277 + 62 NuclAT_15 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_15 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_15 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_15 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_18 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_18 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_18 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_18 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_21 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_21 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_21 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_21 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_24 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_24 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_24 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_24 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_27 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_27 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_27 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_27 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_30 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_30 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_30 - Antitoxin
- (1664216) 1664216..1664277 + 62 NuclAT_30 - Antitoxin
- (1664216) 1664216..1664278 + 63 NuclAT_45 - -
- (1664216) 1664216..1664278 + 63 NuclAT_45 - -
- (1664216) 1664216..1664278 + 63 NuclAT_45 - -
- (1664216) 1664216..1664278 + 63 NuclAT_45 - -
- (1664216) 1664216..1664278 + 63 NuclAT_48 - -
- (1664216) 1664216..1664278 + 63 NuclAT_48 - -
- (1664216) 1664216..1664278 + 63 NuclAT_48 - -
- (1664216) 1664216..1664278 + 63 NuclAT_48 - -
- (1664216) 1664216..1664278 + 63 NuclAT_51 - -
- (1664216) 1664216..1664278 + 63 NuclAT_51 - -
- (1664216) 1664216..1664278 + 63 NuclAT_51 - -
- (1664216) 1664216..1664278 + 63 NuclAT_51 - -
- (1664216) 1664216..1664279 + 64 NuclAT_33 - -
- (1664216) 1664216..1664279 + 64 NuclAT_33 - -
- (1664216) 1664216..1664279 + 64 NuclAT_33 - -
- (1664216) 1664216..1664279 + 64 NuclAT_33 - -
- (1664216) 1664216..1664279 + 64 NuclAT_35 - -
- (1664216) 1664216..1664279 + 64 NuclAT_35 - -
- (1664216) 1664216..1664279 + 64 NuclAT_35 - -
- (1664216) 1664216..1664279 + 64 NuclAT_35 - -
- (1664216) 1664216..1664279 + 64 NuclAT_37 - -
- (1664216) 1664216..1664279 + 64 NuclAT_37 - -
- (1664216) 1664216..1664279 + 64 NuclAT_37 - -
- (1664216) 1664216..1664279 + 64 NuclAT_37 - -
- (1664216) 1664216..1664279 + 64 NuclAT_39 - -
- (1664216) 1664216..1664279 + 64 NuclAT_39 - -
- (1664216) 1664216..1664279 + 64 NuclAT_39 - -
- (1664216) 1664216..1664279 + 64 NuclAT_39 - -
- (1664216) 1664216..1664279 + 64 NuclAT_41 - -
- (1664216) 1664216..1664279 + 64 NuclAT_41 - -
- (1664216) 1664216..1664279 + 64 NuclAT_41 - -
- (1664216) 1664216..1664279 + 64 NuclAT_41 - -
- (1664216) 1664216..1664279 + 64 NuclAT_43 - -
- (1664216) 1664216..1664279 + 64 NuclAT_43 - -
- (1664216) 1664216..1664279 + 64 NuclAT_43 - -
- (1664216) 1664216..1664279 + 64 NuclAT_43 - -
HRS04_RS08945 (1664592) 1664592..1664699 - 108 WP_000170965.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1664747) 1664747..1664812 + 66 NuclAT_14 - -
- (1664747) 1664747..1664812 + 66 NuclAT_14 - -
- (1664747) 1664747..1664812 + 66 NuclAT_14 - -
- (1664747) 1664747..1664812 + 66 NuclAT_14 - -
- (1664747) 1664747..1664812 + 66 NuclAT_17 - -
- (1664747) 1664747..1664812 + 66 NuclAT_17 - -
- (1664747) 1664747..1664812 + 66 NuclAT_17 - -
- (1664747) 1664747..1664812 + 66 NuclAT_17 - -
- (1664747) 1664747..1664812 + 66 NuclAT_20 - -
- (1664747) 1664747..1664812 + 66 NuclAT_20 - -
- (1664747) 1664747..1664812 + 66 NuclAT_20 - -
- (1664747) 1664747..1664812 + 66 NuclAT_20 - -
- (1664747) 1664747..1664812 + 66 NuclAT_23 - -
- (1664747) 1664747..1664812 + 66 NuclAT_23 - -
- (1664747) 1664747..1664812 + 66 NuclAT_23 - -
- (1664747) 1664747..1664812 + 66 NuclAT_23 - -
- (1664747) 1664747..1664812 + 66 NuclAT_26 - -
- (1664747) 1664747..1664812 + 66 NuclAT_26 - -
- (1664747) 1664747..1664812 + 66 NuclAT_26 - -
- (1664747) 1664747..1664812 + 66 NuclAT_26 - -
- (1664747) 1664747..1664812 + 66 NuclAT_29 - -
- (1664747) 1664747..1664812 + 66 NuclAT_29 - -
- (1664747) 1664747..1664812 + 66 NuclAT_29 - -
- (1664747) 1664747..1664812 + 66 NuclAT_29 - -
- (1664748) 1664748..1664813 + 66 NuclAT_46 - -
- (1664748) 1664748..1664813 + 66 NuclAT_46 - -
- (1664748) 1664748..1664813 + 66 NuclAT_46 - -
- (1664748) 1664748..1664813 + 66 NuclAT_46 - -
- (1664748) 1664748..1664813 + 66 NuclAT_49 - -
- (1664748) 1664748..1664813 + 66 NuclAT_49 - -
- (1664748) 1664748..1664813 + 66 NuclAT_49 - -
- (1664748) 1664748..1664813 + 66 NuclAT_49 - -
- (1664748) 1664748..1664813 + 66 NuclAT_52 - -
- (1664748) 1664748..1664813 + 66 NuclAT_52 - -
- (1664748) 1664748..1664813 + 66 NuclAT_52 - -
- (1664748) 1664748..1664813 + 66 NuclAT_52 - -
- (1664747) 1664747..1664814 + 68 NuclAT_32 - -
- (1664747) 1664747..1664814 + 68 NuclAT_32 - -
- (1664747) 1664747..1664814 + 68 NuclAT_32 - -
- (1664747) 1664747..1664814 + 68 NuclAT_32 - -
- (1664747) 1664747..1664814 + 68 NuclAT_34 - -
- (1664747) 1664747..1664814 + 68 NuclAT_34 - -
- (1664747) 1664747..1664814 + 68 NuclAT_34 - -
- (1664747) 1664747..1664814 + 68 NuclAT_34 - -
- (1664747) 1664747..1664814 + 68 NuclAT_36 - -
- (1664747) 1664747..1664814 + 68 NuclAT_36 - -
- (1664747) 1664747..1664814 + 68 NuclAT_36 - -
- (1664747) 1664747..1664814 + 68 NuclAT_36 - -
- (1664747) 1664747..1664814 + 68 NuclAT_38 - -
- (1664747) 1664747..1664814 + 68 NuclAT_38 - -
- (1664747) 1664747..1664814 + 68 NuclAT_38 - -
- (1664747) 1664747..1664814 + 68 NuclAT_38 - -
- (1664747) 1664747..1664814 + 68 NuclAT_40 - -
- (1664747) 1664747..1664814 + 68 NuclAT_40 - -
- (1664747) 1664747..1664814 + 68 NuclAT_40 - -
- (1664747) 1664747..1664814 + 68 NuclAT_40 - -
- (1664747) 1664747..1664814 + 68 NuclAT_42 - -
- (1664747) 1664747..1664814 + 68 NuclAT_42 - -
- (1664747) 1664747..1664814 + 68 NuclAT_42 - -
- (1664747) 1664747..1664814 + 68 NuclAT_42 - -
HRS04_RS08950 (1665104) 1665104..1666204 - 1101 WP_001295620.1 sodium-potassium/proton antiporter ChaA -
HRS04_RS08955 (1666474) 1666474..1666704 + 231 WP_001146442.1 putative cation transport regulator ChaB -
HRS04_RS08960 (1666862) 1666862..1667557 + 696 WP_094658721.1 glutathione-specific gamma-glutamylcyclotransferase -
HRS04_RS08965 (1667601) 1667601..1667954 - 354 WP_001169671.1 DsrE/F sulfur relay family protein YchN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3983.84 Da        Isoelectric Point: 11.6501

>T158859 WP_000170926.1 NZ_CP054169:c1664163-1664056 [Escherichia coli]
MTLAKFAMIFWHDLAAPILAGIITAAIVGWWRNRK

Download         Length: 108 bp

>T158859 NZ_CP069865:2644641-2644814 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 62 bp

>AT158859 NZ_CP054169:1664216-1664277 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0Y1K9

Antitoxin

Download structure file

References