Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3072249..3072772 Replicon chromosome
Accession NZ_CP054058
Organism Scandinavium goeteborgense strain CCUG 66741

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag A8O29_RS15625 Protein ID WP_125354533.1
Coordinates 3072249..3072509 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag A8O29_RS15630 Protein ID WP_125354532.1
Coordinates 3072506..3072772 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8O29_RS15605 3069244..3070170 - 927 WP_168713865.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
A8O29_RS15610 3070263..3070877 + 615 WP_125354534.1 flavin reductase family protein -
A8O29_RS15615 3071040..3071303 + 264 WP_110510015.1 DUF1471 domain-containing protein -
A8O29_RS15620 3071750..3072010 + 261 WP_110510016.1 DUF1471 domain-containing protein -
A8O29_RS15625 3072249..3072509 - 261 WP_125354533.1 Txe/YoeB family addiction module toxin Toxin
A8O29_RS15630 3072506..3072772 - 267 WP_125354532.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
A8O29_RS15635 3072870..3073838 - 969 WP_125354531.1 DNA-binding protein YbiB -
A8O29_RS15640 3073868..3076018 - 2151 WP_174081362.1 ATP-dependent DNA helicase DinG -
A8O29_RS15645 3076122..3077522 - 1401 WP_125354530.1 ATP-dependent RNA helicase RhlE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10054.78 Da        Isoelectric Point: 9.5623

>T158623 WP_125354533.1 NZ_CP054058:c3072509-3072249 [Scandinavium goeteborgense]
MKVAFTAQAKADLLHWLEAEPTVKDKIDKLICNALQDPRTGIGKPEALKHHKPLWSRRITKEHRLVYYVQDDTLMVVSCR
FHYINL

Download         Length: 261 bp

>T158623 NZ_CP069706:1754102-1754353 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9677.80 Da        Isoelectric Point: 4.3547

>AT158623 WP_125354532.1 NZ_CP054058:c3072772-3072506 [Scandinavium goeteborgense]
MQHVNYTDARQNLAQLMQQANDDRAPILVTRKGSKSVVVIDADEFAAIQETLHLFGNPANAAVLTKSLEQADSGDVFEYD
PVKGTFIE

Download         Length: 267 bp

>AT158623 NZ_CP069706:1754350-1754604 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAATGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References