Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 938068..938229 Replicon chromosome
Accession NZ_CP054017
Organism Staphylococcus warneri strain FDAARGOS_754

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag FOC62_RS04615 Protein ID WP_015364873.1
Coordinates 938134..938229 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 938068..938102 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC62_RS04590 934064..934804 - 741 WP_002452116.1 ABC transporter ATP-binding protein -
FOC62_RS04595 934936..935361 + 426 WP_002452115.1 HIT family protein -
FOC62_RS04600 935439..935810 + 372 WP_002452114.1 YtxH domain-containing protein -
FOC62_RS04605 936004..936561 + 558 WP_002452113.1 DUF3267 domain-containing protein -
FOC62_RS04610 936990..937982 + 993 WP_002452112.1 peptidylprolyl isomerase -
- 938068..938102 + 35 - - Antitoxin
FOC62_RS04615 938134..938229 - 96 WP_015364873.1 type I toxin-antitoxin system Fst family toxin Toxin
FOC62_RS04620 938381..939322 - 942 WP_002452110.1 3'-5' exoribonuclease YhaM -
FOC62_RS04625 939322..942255 - 2934 WP_002452109.1 AAA family ATPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-35)


Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3610.26 Da        Isoelectric Point: 8.0878

>T158517 WP_015364873.1 NZ_CP054017:c938229-938134 [Staphylococcus warneri]
MTEIFVHIATTVISGCIVTLFAHWLRHRNDK

Download         Length: 96 bp

>T158517 NZ_CP069657:2799197-2799304 [Escherichia coli O89m:H10]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 35 bp

>AT158517 NZ_CP054017:938068-938102 [Staphylococcus warneri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References