Detailed information of TA system TA158356

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1022555..1022717
• Replicon: chromosome
• Accession: NZ_CP053957
• Organism: Staphylococcus capitis strain FDAARGOS_753

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: FOC61_RS05050
• Protein ID: WP_016898319.1
• Coordinates: 1022555..1022659 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1022687..1022717 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FOC61_RS05040	1018487..1021426	+	2940	WP_002453570.1	AAA family ATPase	-
FOC61_RS05045	1021423..1022364	+	942	WP_002434737.1	3'-5' exoribonuclease YhaM	-
FOC61_RS05050	1022555..1022659	+	105	WP_016898319.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1022687..1022717	+	31	-	-	Antitoxin
FOC61_RS05055	1022814..1023815	-	1002	WP_002453569.1	peptidylprolyl isomerase	-
FOC61_RS05060	1024015..1024584	-	570	WP_002453568.1	DUF3267 domain-containing protein	-
FOC61_RS05065	1024776..1025147	-	372	WP_002434824.1	YtxH domain-containing protein	-
FOC61_RS05070	1025225..1025650	-	426	WP_002434751.1	HIT family protein	-
FOC61_RS05075	1025783..1026523	+	741	WP_002453567.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1005989..1091676	85687

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3993.76 Da
• Isoelectric Point: 10.7588

>T158356 WP_016898319.1 NZ_CP053957:1022555-1022659 [Staphylococcus capitis]
MLFDIFVHIMTTATSGCIVALFAHWLRTRNDKRK

Nucleotide

• Length: 105 bp

>T158356 NZ_CP069627:1802210-1802587 [Escherichia coli]
ATGAAAACATTACCCGACACACACGTACGGGCGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCAGGTACGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA

Antitoxin

Nucleotide

• Length: 31 bp

>AT158356 NZ_CP053957:1022687-1022717 [Staphylococcus capitis]
AAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin