Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 57764..58469 Replicon chromosome
Accession NZ_CP053748
Organism Massilia sp. erpn

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag HPQ68_RS00255 Protein ID WP_255755916.1
Coordinates 57764..58066 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag HPQ68_RS00260 Protein ID WP_255755917.1
Coordinates 58068..58469 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPQ68_RS00225 (HPQ68_00225) 53141..53443 - 303 WP_050408858.1 ATP-dependent Clp protease adapter ClpS -
HPQ68_RS00230 (HPQ68_00230) 53768..53971 + 204 WP_050408859.1 cold-shock protein -
HPQ68_RS00235 (HPQ68_00235) 54032..55240 - 1209 WP_255755912.1 citrate synthase family protein -
HPQ68_RS00240 (HPQ68_00240) 55342..56595 + 1254 WP_255755913.1 MFS transporter -
HPQ68_RS00245 (HPQ68_00245) 56592..57113 + 522 WP_255755914.1 GNAT family protein -
HPQ68_RS00250 (HPQ68_00250) 57126..57680 - 555 WP_255755915.1 GNAT family N-acetyltransferase -
HPQ68_RS00255 (HPQ68_00255) 57764..58066 + 303 WP_255755916.1 type II toxin-antitoxin system MqsR family toxin Toxin
HPQ68_RS00260 (HPQ68_00260) 58068..58469 + 402 WP_255755917.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
HPQ68_RS00265 (HPQ68_00265) 58551..59804 - 1254 WP_176348164.1 NADP-dependent isocitrate dehydrogenase -
HPQ68_RS00270 (HPQ68_00270) 59968..60534 + 567 WP_255755918.1 pseudouridine synthase -
HPQ68_RS00275 (HPQ68_00275) 60678..60911 + 234 WP_255755919.1 hypothetical protein -
HPQ68_RS00280 (HPQ68_00280) 61040..61480 + 441 WP_255755920.1 DUF192 domain-containing protein -
HPQ68_RS00285 (HPQ68_00285) 61606..61872 - 267 WP_050408868.1 30S ribosomal protein S20 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-99)

Antitoxin

Antitoxin MqsA

(4-132)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10798.60 Da        Isoelectric Point: 7.9067

>T157697 WP_255755916.1 NZ_CP053748:57764-58066 [Massilia sp. erpn]
MEKGTPHCKLPRIKALIEAGQVTATASATISARALGINTLQGMCDVILSLTGADFYKSMTAHANHQIWQDVYHGRTADGI
ALYIKLTVIADVLIVSFKEL

Download         Length: 303 bp

>T157697 NZ_CP069447:2823889-2825211 [Escherichia coli]
ATGCCTAAACTAGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCTGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGATAGCGTTGGTGCCGTGACGTTAATCCCCGAAGA
TGAAACCGTAACGTGTCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGTTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACTGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAGGGAATAACGCCAACGACGCACATTATCAAATTGCCGATTGGCGAAAT
CAGACAGCCCAATGCGACGCTCGATCTTAGCCAAAGCGTTGATAATGAGTATTACTGTTTGCTGCTGGCGAAAGAACTCG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCAAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGCCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCCGGTATCGCGCAAATTATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTCTTCCAGTGGTTGATTGGCGCAACAGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGGCTCACACCATTTTATGACATCATTTCGGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGAATTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGGTCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14852.91 Da        Isoelectric Point: 8.1452

>AT157697 WP_255755917.1 NZ_CP053748:58068-58469 [Massilia sp. erpn]
MKNCPGCGAPSPAHATRDMPYTYKGQNTVIPAVRGYHCASCGEVTLDHDAVDRFSELLGEFQRKVNSELVDPAYILTVRR
KLRLDQREAGEIFGGGANAFSRYETGKARPHISTIKLLKLLDRHPELLDEVRQ

Download         Length: 402 bp

>AT157697 NZ_CP069447:2823623-2823889 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAACGGCTGGAC
GCAGAGCGAGTTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAATCCTGACAATACCTCGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAAGCA
GCAGAACAGCAAGATTTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References