157280

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2394493..2394677 Replicon chromosome
Accession NZ_CP053636
Organism Staphylococcus aureus strain 14640

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag HA037_RS11755 Protein ID WP_000482652.1
Coordinates 2394493..2394600 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2394617..2394677 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HA037_RS11730 2389855..2390328 + 474 WP_000456486.1 GyrI-like domain-containing protein -
HA037_RS11735 2390451..2391662 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
HA037_RS11740 2391844..2392503 - 660 WP_000831298.1 membrane protein -
HA037_RS11745 2392563..2393705 - 1143 WP_001176863.1 glycerate kinase -
HA037_RS11750 2393973..2394359 + 387 WP_000779360.1 flippase GtxA -
HA037_RS11755 2394493..2394600 + 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2394617..2394677 - 61 - - Antitoxin
HA037_RS11760 2395303..2397066 + 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
HA037_RS11765 2397091..2398824 + 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
HA037_RS11770 2399055..2399222 + 168 Protein_2288 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T157280 WP_000482652.1 NZ_CP053636:2394493-2394600 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T157280 NZ_CP053636:2394493-2394600 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT157280 NZ_CP053636:c2394677-2394617 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References