Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3090233..3090455 Replicon chromosome
Accession NZ_CP053603
Organism Escherichia coli strain Dam/Dcm

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag HO395_RS14925 Protein ID WP_000141634.1
Coordinates 3090348..3090455 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3090233..3090299 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HO395_RS14905 3085674..3086576 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
HO395_RS14910 3086587..3087570 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
HO395_RS14915 3087567..3088571 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
HO395_RS14920 3088601..3089872 - 1272 WP_001295225.1 transporter -
- 3090233..3090299 - 67 - - Antitoxin
HO395_RS14925 3090348..3090455 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
HO395_RS14930 3090542..3092221 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
HO395_RS14935 3092218..3092409 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
HO395_RS14940 3092406..3093977 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
HO395_RS14945 3094250..3094438 + 189 WP_001063318.1 YhjR family protein -
HO395_RS14950 3094450..3095202 + 753 Protein_2915 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T157080 WP_000141634.1 NZ_CP053603:3090348-3090455 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T157080 NZ_CP053603:3090348-3090455 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT157080 NZ_CP053603:c3090299-3090233 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References