Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 122398..122900 Replicon plasmid unnamed1
Accession NZ_CP053574
Organism Citrobacter sp. TSA-1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HF677_RS23890 Protein ID WP_095715681.1
Coordinates 122398..122652 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HF677_RS23895 Protein ID WP_095715682.1
Coordinates 122649..122900 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF677_RS23875 119340..121538 - 2199 WP_095715680.1 type IV conjugative transfer system coupling protein TraD -
HF677_RS23880 121678..121893 + 216 Protein_120 toxin-antitoxin system antitoxin VapB -
HF677_RS23885 121903..122301 + 399 Protein_121 tRNA(fMet)-specific endonuclease VapC -
HF677_RS23890 122398..122652 - 255 WP_095715681.1 type II toxin-antitoxin system mRNA interferase toxin YoeB Toxin
HF677_RS23895 122649..122900 - 252 WP_095715682.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
HF677_RS23900 123139..123894 - 756 WP_095715683.1 complement resistance protein TraT -
HF677_RS23905 124032..124946 - 915 WP_095715684.1 hypothetical protein -
HF677_RS23910 124960..127812 - 2853 WP_095715685.1 conjugal transfer mating pair stabilization protein TraG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - vipA/tssB / vipB/tssC / hcp/tssD / clpV/tssH / pefD / rck / pefD 1..171562 171562


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10147.52 Da        Isoelectric Point: 8.0353

>T156882 WP_095715681.1 NZ_CP053574:c122652-122398 [Citrobacter sp. TSA-1]
VKLTWSEEAWDDYLYWQETDKRMVKKINELIKDTRRTAFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAAC
RYHY

Download         Length: 255 bp

>T156882 NZ_CP069072:2930726-2931166 [Mycobacterium tuberculosis]
ATGCTGCTCTGTGACACCAACATCTGGCTGGCGTTGGCGCTTTCCGGACACGTGCACCACAGGGCCTCGCGCGCATGGCT
AGACACCATCAACGCGCCCGGAGTCATCCACTTTTGCCGCGCAACCCAACAGTCGCTCCTTCGGCTGTTGACGAATCGGA
CGGTGCTGGGCGCGTATGGCAGCCCACCACTGACCAACCGCGAAGCGTGGGCGGCCTATGCCGCGTTCCTGGATGACGAC
CGCATCGTGCTGGCCGGCGCCGAACCTGATGGTTTGGAGGCCCAGTGGAGAGCCTTCGCCGTTCGCCAGTCGCCGGCGCC
CAAGGTTTGGATGGATGCCTACCTAGCTGCTTTCGCACTTACCGGTGGATTCGAGTTGGTGACGACTGACACCGCCTTCA
CCCAGTACGGCGGAATCGAGCTGCGGCTCCTGGCCAAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9336.61 Da        Isoelectric Point: 4.5843

>AT156882 WP_095715682.1 NZ_CP053574:c122900-122649 [Citrobacter sp. TSA-1]
MRTISYSEARQNLSATMLKTVEDNAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANARRLMDSIDSLKSGRGIEKD
IIE

Download         Length: 252 bp

>AT156882 NZ_CP069072:2930452-2930739 [Mycobacterium tuberculosis]
ATGAAGACCACGCTCGACCTGCCTGATGAACTGATGCGCGCTATCAAGGTCCGCGCGGCGCAGCAGGGCCGCAAGATGAA
AGATGTCGTGACCGAACTGCTCAGATCCGGTCTGTCCCAGACGCACAGCGGGGCTCCAATCCCAACGCCGCGGCGCGTGC
AGCTTCCCCTGGTGCATTGCGGTGGCGCGGCTACCCGCGAACAAGAAATGACGCCGGAGCGTGTTGCCGCGGCCTTGCTC
GACCAGGAGGCCCAGTGGTGGTCCGGACACGACGATGCTGCTCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References